Lipid nanocapsules: a new platform for nanomedicine
NT Huynh, C Passirani, P Saulnier, JP Benoît - International journal of …, 2009 - Elsevier
Nanomedicine, an emerging new field created by the fusion of nanotechnology and
medicine, is one of the most promising pathways for the development of effective targeted …
medicine, is one of the most promising pathways for the development of effective targeted …
Convection-enhanced delivery of nanocarriers for the treatment of brain tumors
E Allard, C Passirani, JP Benoit - Biomaterials, 2009 - Elsevier
Primary brain tumors have a significant infiltrative capacity as their reappearance after
resection usually occurs within 2cm of the tumor margin. Local delivery method such as …
resection usually occurs within 2cm of the tumor margin. Local delivery method such as …
Blood-brain barrier disruption with focused ultrasound enhances delivery of chemotherapeutic drugs for glioblastoma treatment
Purpose To demonstrate the feasibility of using focused ultrasound to enhance delivery of 1,
3-bis (2-chloroethyl)-1-nitrosourea (BCNU) to glioblastomas in rats with induced tumors and …
3-bis (2-chloroethyl)-1-nitrosourea (BCNU) to glioblastomas in rats with induced tumors and …
[HTML][HTML] A perspective on the radiopharmaceutical requirements for imaging and therapy of glioblastoma
J Bolcaen, J Kleynhans, S Nair, J Verhoeven… - Theranostics, 2021 - ncbi.nlm.nih.gov
Despite numerous clinical trials and pre-clinical developments, the treatment of glioblastoma
(GB) remains a challenge. The current survival rate of GB averages one year, even with an …
(GB) remains a challenge. The current survival rate of GB averages one year, even with an …
Convection‐enhanced drug delivery to the brain: Therapeutic potential and neuropathological considerations
Convection‐enhanced delivery (CED) describes a direct method of drug delivery to the brain
through intraparenchymal microcatheters. By establishing a pressure gradient at the tip of …
through intraparenchymal microcatheters. By establishing a pressure gradient at the tip of …
Lipid nanocapsules to enhance drug bioavailability to the central nervous system
The central nervous system (CNS), namely the brain, still remains as the hardest area of the
human body to achieve adequate concentration levels of most drugs, mainly due to the …
human body to achieve adequate concentration levels of most drugs, mainly due to the …
Transferrin adsorption onto PLGA nanoparticles governs their interaction with biological systems from blood circulation to brain cancer cells
J Chang, A Paillard, C Passirani, M Morille… - Pharmaceutical …, 2012 - Springer
Purpose Nanomedicines represent an alternative for the treatment of aggressive
glioblastoma tumors. Behaviour of PLGA-nanoparticles (NPs) was here investigated as a …
glioblastoma tumors. Behaviour of PLGA-nanoparticles (NPs) was here investigated as a …
The radiosensitization effect of titanate nanotubes as a new tool in radiation therapy for glioblastoma: a proof-of-concept
Background and purpose One of the new challenges to improve radiotherapy is to increase
the ionizing effect by using nanoparticles. The interest of titanate nanotubes (TiONts) …
the ionizing effect by using nanoparticles. The interest of titanate nanotubes (TiONts) …
Nanotherapeutic systems for local treatment of brain tumors
Malignant brain tumor, including the most common type glioblastoma, are histologically
heterogeneous and invasive tumors known as the most devastating neoplasms with high …
heterogeneous and invasive tumors known as the most devastating neoplasms with high …
Image-guided interventional therapy for cancer with radiotherapeutic nanoparticles
One of the major limitations of current cancer therapy is the inability to deliver tumoricidal
agents throughout the entire tumor mass using traditional intravenous administration …
agents throughout the entire tumor mass using traditional intravenous administration …