The adoption of “artificial intelligence (AI) in drug discovery”, where AI is used in the process
of pharmaceutical research and development, is progressing. By using the ability to process …

Proper vertebrae formation relies on a tissue-wide oscillator called the segmentation clock.
Individual cellular oscillators in the presomitic mesoderm are modulated by intercellular …

The expression of a few key genes determines the body plan of the fruit fly. We show that the
spatial expression patterns for several of these genes scale precisely with embryo size …

Many biological systems operate near the physical limits to their performance, suggesting
that aspects of their behavior and underlying mechanisms could be derived from …

Networks in machine learning offer examples of complex high-dimensional dynamical
systems inspired by and reminiscent of biological systems. Here, we study the learning …

Transcription factor combinations play a key role in sha** cellular identity. However, the
precise relationship between specific combinations and downstream effects remains …

Chemical waves represent one of the fundamental behaviors that emerge in nonlinear, out-
of-equilibrium chemical systems. They also play a central role in regulating behaviors and …

Signal transduction is crucial for many biological functions. However, it is still unclear how
signaling systems function accurately under noisy situations. More specifically, such systems …

There is a long history of theory for biology, initially as a way to provide explanatory and
conceptual frameworks. For example, in evolution, natural selection offers an explanation for …

Gene expression patterns in develo** organisms are established by groups of cross-
regulating target genes that are driven by morphogen gradients. As development …