Regulation of glucose and lipid metabolism in health and disease

L Chen, XW Chen, X Huang, BL Song, Y Wang… - Science China life …, 2019‏ - Springer
Glucose and fatty acids are the major sources of energy for human body. Cholesterol, the
most abundant sterol in mammals, is a key component of cell membranes although it does …

Cholesterol and lipoprotein metabolism and atherosclerosis: recent advances in reverse cholesterol transport

HH Wang, G Garruti, M Liu, P Portincasa… - Annals of …, 2018‏ - medigraphic.com
Atherosclerosis is characterized by lipid accumulation, inflammatory response, cell death
and fibrosis in the arterial wall, and is a major pathological basis for ischemic coronary heart …

An update on the pathogenesis of cholesterol gallstone disease

A Di Ciaula, DQH Wang… - Current opinion in …, 2018‏ - journals.lww.com
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[HTML][HTML] Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease

H Gylling, J Plat, S Turley, HN Ginsberg, L Ellegård… - Atherosclerosis, 2014‏ - Elsevier
Abstract Objective This EAS Consensus Panel critically appraised evidence relevant to the
benefit to risk relationship of functional foods with added plant sterols and/or plant stanols …

[HTML][HTML] Recent molecular mechanisms and beneficial effects of phytochemicals and plant-based whole foods in reducing LDL-C and preventing cardiovascular …

SU Islam, MB Ahmed, H Ahsan, YS Lee - Antioxidants, 2021‏ - mdpi.com
Abnormal lipid metabolism leads to the development of hyperlipidemia, a common cause of
multiple chronic disorders, including cardiovascular disease (CVD), obesity, diabetes, and …

Cellular cholesterol trafficking and compartmentalization

E Ikonen - Nature reviews Molecular cell biology, 2008‏ - nature.com
Cholesterol is an essential structural component in the cell membranes of most vertebrates.
The biophysical properties of cholesterol and the enzymology of cholesterol metabolism …

Mechanisms underlying the cholesterol-lowering properties of soluble dietary fibre polysaccharides

P Gunness, MJ Gidley - Food & function, 2010‏ - pubs.rsc.org
A number of studies have shown a positive relationship between diets rich in soluble dietary
fibres (SDF) such as β-glucan, pectin, guar gum and psyllium, and reduced serum …

New insights into the molecular mechanism of intestinal fatty acid absorption

TY Wang, M Liu, P Portincasa… - European journal of …, 2013‏ - Wiley Online Library
Background Dietary fat is one of the most important energy sources of all the nutrients. Fatty
acids, stored as triacylglycerols (also called triglycerides) in the body, are an important …

Niemann-pick C1-like 1 (NPC1L1) protein in intestinal and hepatic cholesterol transport

L Jia, JL Betters, L Yu - Annual review of physiology, 2011‏ - annualreviews.org
Increased blood cholesterol is an independent risk factor for atherosclerotic cardiovascular
disease. Cholesterol homeostasis in the body is controlled mainly by endogenous synthesis …

Molecular pathways underlying cholesterol homeostasis

MS Afonso, RM Machado, MS Lavrador, ECR Quintao… - Nutrients, 2018‏ - mdpi.com
Cholesterol is an essential molecule that exerts pleiotropic actions. Although its presence is
vital to the cell, its excess can be harmful and, therefore, sustaining cholesterol homeostasis …