Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are uniquely
required to balance the formation of new blood vessels with the maintenance and …

The endothelium is capable of remarkable plasticity. In the embryo, primitive endothelial
cells differentiate to acquire arterial, venous or lymphatic fates. Certain endothelial cells also …

In addition to their conventional role as a conduit system for gases, nutrients, waste products
or cells, blood vessels in the skeletal system play active roles in controlling multiple aspects …

The sites of targeted therapy are limited and need to be expanded. The FGF‐FGFR
signalling plays pivotal roles in the oncogenic process, and FGF/FGFR inhibitors are a …

Objective Macrophages show extreme heterogeneity and different subsets have been
characterized by their activation route and their function. For instance, macrophage subsets …

Endothelial cells are at the interface between circulating blood and tissues. This position
confers on them a crucial role in controlling oxygen and nutrient exchange and cellular …

Simple Summary Tumor growth in solid cancers requires adequate nutrient and oxygen
supply, provided by blood vessels created by angiogenesis. Numerous studies have …

Rationale: Emerging evidence indicates that the growth of blood vessels and osteogenesis
is tightly coordinated during bone development. However, the molecular regulators of …

To identify pathways involved in adult lung regeneration, we employ a unilateral
pneumonectomy (PNX) model that promotes regenerative alveolarization in the remaining …

Angiogenesis contributes fundamentally to embryonic development, tissue homeostasis,
and wound healing. Basic fibroblast growth factor (FGF2) is recognized as the first …