Executive control is a complex high-level cognitive function that relies on distributed brain
circuitry. We propose that the anterior insular cortex plays an under-appreciated role in …

Emotions are fundamental to our experience and behavior, affecting and motivating all
aspects of our lives. Scientists of various disciplines have been fascinated by emotions for …

This paper formulates the action of psychedelics by integrating the free-energy principle and
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …

This review considers computational psychiatry from a particular viewpoint: namely, a
commitment to explaining psychopathology in terms of pathophysiology. It rests on the …

Scholars have argued for centuries that affective states involve interoception, or
representations of the state of the body. Yet, we lack a mechanistic understanding of how …

Functional neurological disorder reflects impairments in brain networks leading to
distressing motor, sensory and/or cognitive symptoms that demonstrate positive clinical …

This paper describes a path integral formulation of the free energy principle. The ensuing
account expresses the paths or trajectories that a particle takes as it evolves over time. The …

Prominent accounts of sentient behavior depict brains as generative models of organismic
interaction with the world, evincing intriguing similarities with current advances in generative …

We review recent work on the functions of interoceptive processing, by which the nervous
system anticipates, senses, and integrates signals originating from the body. We focus on …

A new theory about the origins of consciousness that finds learning to be the driving force in
the evolutionary transition to basic consciousness. What marked the evolutionary transition …