Near infrared photoimmunotherapy: a review of recent progress and their target molecules for cancer therapy

TM Mohiuddin, C Zhang, W Sheng, M Al-Rawe… - International journal of …, 2023‏ - mdpi.com
Near infrared photoimmunotherapy (NIR-PIT) is a newly developed molecular targeted
cancer treatment, which selectively kills cancer cells or immune-regulatory cells and induces …

[HTML][HTML] Near infrared photoimmunotherapy; a review of targets for cancer therapy

T Kato, H Wakiyama, A Furusawa, PL Choyke… - Cancers, 2021‏ - mdpi.com
Simple Summary Near-infrared photoimmunotherapy (NIR-PIT) is a newly developed cancer
treatment that uses an antibody-photoabsorber (IRDye700DX) conjugate (APC) that is …

Treg-dominant tumor microenvironment is responsible for hyperprogressive disease after PD-1 blockade therapy

H Wakiyama, T Kato, A Furusawa… - Cancer Immunology …, 2022‏ - aacrjournals.org
Abstract Programmed cell death 1 (PD-1) blockade therapy can result in dramatic responses
in some patients with cancer. However, about 15% of patients receiving PD-1 blockade …

Phototruncation cell tracking with near-infrared photoimmunotherapy using heptamethine cyanine dye to visualise migratory dynamics of immune cells

H Fukushima, A Furusawa, S Takao, SS Matikonda… - …, 2024‏ - thelancet.com
Background Noninvasive in vivo cell tracking is valuable in understanding the mechanisms
that enhance anti-cancer immunity. We have recently developed a new method called …

Near infrared photoimmunotherapy for cancers: A translational perspective

Y Maruoka, H Wakiyama, PL Choyke, H Kobayashi - EBioMedicine, 2021‏ - thelancet.com
Near-infrared photoimmunotherapy (NIR-PIT) is a newly-developed, highly-selective cancer
treatment, which utilizes a monoclonal antibody conjugated to a photoabsorbing dye …

Quickly evolving near‐infrared photoimmunotherapy provides multifaceted approach to modern cancer treatment

H Monaco, S Yokomizo, HS Choi, S Kashiwagi - View, 2022‏ - Wiley Online Library
Among modalities of cancer immunotherapy, near‐infrared photoimmunotherapy (NIR‐PIT)
has reached significant preclinical and clinical stages and quickly evolved over the last 5 …

The mouse oral carcinoma (MOC) model: a 10-year retrospective on model development and head and neck cancer investigations

M Kono, S Saito, AM Egloff, CT Allen, R Uppaluri - Oral oncology, 2022‏ - Elsevier
Preclinical models of cancer have long been paramount to understanding tumor
development and advancing the treatment of cancer. Creating preclinical models that mimic …

Adrenergic receptor signaling regulates the CD40-receptor mediated anti-tumor immunity

A Singh, A Ranjan - Frontiers in immunology, 2023‏ - frontiersin.org
Introduction Anti-CD40 agonistic antibody (αCD40), an activator of dendritic cells (DC) can
enhance antigen presentation and activate cytotoxic T-cells against poorly immunogenic …

Simultaneously combined cancer cell-and CTLA4-targeted NIR-PIT causes a synergistic treatment effect in syngeneic mouse models

T Kato, R Okada, A Furusawa, F Inagaki… - Molecular cancer …, 2021‏ - aacrjournals.org
Near-infrared photoimmunotherapy (NIR-PIT) is a new cancer treatment that utilizes
antibody–IRDye700DX (IR700) conjugates. The clinical use of NIR-PIT has recently been …

Near‐infrared photoimmunotherapy targeting PD‐L1: Improved efficacy by preconditioning the tumor microenvironment

FF Inagaki, M Kano, A Furusawa, T Kato… - Cancer …, 2024‏ - Wiley Online Library
Near‐infrared photoimmunotherapy (NIR‐PIT) is a new type of cancer therapy that employs
antibody‐IRDye700DX conjugates (AbPCs) and near‐infrared (NIR) light at a wavelength of …