Adaptive laboratory evolution–principles and applications for biotechnology
M Dragosits, D Mattanovich - Microbial cell factories, 2013 - Springer
Adaptive laboratory evolution is a frequent method in biological studies to gain insights into
the basic mechanisms of molecular evolution and adaptive changes that accumulate in …
the basic mechanisms of molecular evolution and adaptive changes that accumulate in …
Functional comparison of metabolic networks across species
C Ramon, J Stelling - Nature Communications, 2023 - nature.com
Metabolic phenotypes are pivotal for many areas, but disentangling how evolutionary history
and environmental adaptation shape these phenotypes is an open problem. Especially for …
and environmental adaptation shape these phenotypes is an open problem. Especially for …
The role of cellular objectives and selective pressures in metabolic pathway evolution
Evolution results from molecular-level changes in an organism, thereby producing novel
phenotypes and, eventually novel species. However, changes in a single gene can lead to …
phenotypes and, eventually novel species. However, changes in a single gene can lead to …
Gene-centric association analysis for the correlation between the guanine-cytosine content levels and temperature range conditions of prokaryotic species
H Zheng, H Wu - BMC bioinformatics, 2010 - Springer
Background The environment has been playing an instrumental role in sha** and
maintaining the morphological, physiological and biochemical diversities of prokaryotes. It …
maintaining the morphological, physiological and biochemical diversities of prokaryotes. It …
Evolution of metabolic network organization
Background Comparison of metabolic networks across species is a key to understanding
how evolutionary pressures shape these networks. By selecting taxa representative of …
how evolutionary pressures shape these networks. By selecting taxa representative of …
The Genome Organization of Thermotoga maritima Reflects Its Lifestyle
The generation of genome-scale data is becoming more routine, yet the subsequent
analysis of omics data remains a significant challenge. Here, an approach that integrates …
analysis of omics data remains a significant challenge. Here, an approach that integrates …
Functional prediction of environmental variables using metabolic networks
A Weber Zendrera, N Sokolovska, HA Soula - Scientific Reports, 2021 - nature.com
In this manuscript, we propose a novel approach to assess relationships between
environment and metabolic networks. We used a comprehensive dataset of more than 5000 …
environment and metabolic networks. We used a comprehensive dataset of more than 5000 …
A critical view of metabolic network adaptations
There has been considerable recent interest in deciphering the adaptive properties
underlying the structure and function of metabolic networks. Various features of metabolic …
underlying the structure and function of metabolic networks. Various features of metabolic …
Exploring temporal transcription regulation structure of Aspergillus fumigatus in heat shock by state space model
JH Do, R Yamaguchi, S Miyano - BMC genomics, 2009 - Springer
Abstract Background The thermotolerance of Aspergillus fumigatus plays a critical role in
mammalian and avian infections. Thus, the identification of its adaptation mechanism to …
mammalian and avian infections. Thus, the identification of its adaptation mechanism to …
Utilization of correlation network analysis to identify differences in sensory attributes and organoleptic compositions of tomato cultivars grown under salt stress
K Zushi, N Matsuzoe - Scientia Horticulturae, 2011 - Elsevier
In tomato production, salt stress is applied to improve the fruit quality. The change in sensory
attributes and organoleptic compositions in salt-stressed tomato fruits have been extensively …
attributes and organoleptic compositions in salt-stressed tomato fruits have been extensively …