Origins of modern human ancestry
New finds in the palaeoanthropological and genomic records have changed our view of the
origins of modern human ancestry. Here we review our current understanding of how the …
origins of modern human ancestry. Here we review our current understanding of how the …
High‐throughput DNA sequencing–concepts and limitations
Recent advances in DNA sequencing have revolutionized the field of genomics, making it
possible for even single research groups to generate large amounts of sequence data very …
possible for even single research groups to generate large amounts of sequence data very …
The complete genome sequence of a Neanderthal from the Altai Mountains
We present a high-quality genome sequence of a Neanderthal woman from Siberia. We
show that her parents were related at the level of half-siblings and that mating among close …
show that her parents were related at the level of half-siblings and that mating among close …
A draft sequence of the Neandertal genome
Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of
Europe and western Asia before disappearing 30,000 years ago. We present a draft …
Europe and western Asia before disappearing 30,000 years ago. We present a draft …
Million-year-old DNA sheds light on the genomic history of mammoths
Temporal genomic data hold great potential for studying evolutionary processes such as
speciation. However, sampling across speciation events would, in many cases, require …
speciation. However, sampling across speciation events would, in many cases, require …
A high-coverage genome sequence from an archaic Denisovan individual
We present a DNA library preparation method that has allowed us to reconstruct a high-
coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The …
coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The …
Reconstructing mitochondrial genomes directly from genomic next-generation sequencing reads—a baiting and iterative map** approach
We present an in silico approach for the reconstruction of complete mitochondrial genomes
of non-model organisms directly from next-generation sequencing (NGS) data …
of non-model organisms directly from next-generation sequencing (NGS) data …
Ancient human genomes suggest three ancestral populations for present-day Europeans
We sequenced the genomes of a∼ 7,000-year-old farmer from Germany and eight∼ 8,000-
year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other …
year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other …
Genetic history of an archaic hominin group from Denisova Cave in Siberia
Using DNA extracted from a finger bone found in Denisova Cave in southern Siberia, we
have sequenced the genome of an archaic hominin to about 1.9-fold coverage. This …
have sequenced the genome of an archaic hominin to about 1.9-fold coverage. This …
A high-coverage Neandertal genome from Vindija Cave in Croatia
To date, the only Neandertal genome that has been sequenced to high quality is from an
individual found in Southern Siberia. We sequenced the genome of a female Neandertal …
individual found in Southern Siberia. We sequenced the genome of a female Neandertal …