Adaptive optics for high-resolution imaging

KM Hampson, R Turcotte, DT Miller… - Nature Reviews …, 2021 - nature.com
Adaptive optics (AO) is a technique that corrects for optical aberrations. It was originally
proposed to correct for the blurring effect of atmospheric turbulence on images in ground …

Review of adaptive optics OCT (AO-OCT): principles and applications for retinal imaging

M Pircher, RJ Zawadzki - Biomedical optics express, 2017 - opg.optica.org
In vivo imaging of the human retina with a resolution that allows visualization of cellular
structures has proven to be essential to broaden our knowledge about the physiology of this …

High-speed and widefield handheld swept-source OCT angiography with a VCSEL light source

S Ni, X Wei, R Ng, S Ostmo, MF Chiang… - Biomedical optics …, 2021 - opg.optica.org
Optical coherence tomography (OCT) and OCT angiography (OCTA) enable noninvasive
structural and angiographic imaging of the eye. Portable handheld OCT/OCTA systems are …

Real-time retinal layer segmentation of OCT volumes with GPU accelerated inferencing using a compressed, low-latency neural network

S Borkovkina, A Camino, W Janpongsri… - Biomedical optics …, 2020 - opg.optica.org
Segmentation of retinal layers in optical coherence tomography (OCT) is an essential step in
OCT image analysis for screening, diagnosis, and assessment of retinal disease …

Application of adaptive optics in ophthalmology

L Liu, Z Wu, M Qi, Y Li, M Zhang, D Liao, P Gao - Photonics, 2022 - mdpi.com
The eye, the photoreceptive organ used to perceive the external environment, is of great
importance to humans. It has been proven that some diseases in humans are accompanied …

Wavefront sensor-less adaptive optics using deep reinforcement learning

E Durech, W Newberry, J Franke… - Biomedical optics …, 2021 - opg.optica.org
Image degradation due to wavefront aberrations can be corrected with adaptive optics (AO).
In a typical AO configuration, the aberrations are measured directly using a Shack-Hartmann …

Manifestation of aberrations in full-field optical coherence tomography

V Barolle, J Scholler, P Mecê, JM Chassot, K Groux… - Optics …, 2021 - opg.optica.org
We report on a theoretical model for image formation in full-field optical coherence
tomography (FFOCT). Because the spatial incoherence of the illumination acts as a virtual …

Large field of view aberrations correction with deformable lenses and multi conjugate adaptive optics

T Furieri, A Bassi, S Bonora - Journal of Biophotonics, 2023 - Wiley Online Library
Optical microscopes can have limited resolution due to aberrations caused by samples and
sample holders. Using deformable mirrors and wavefront sensorless optimization algorithms …

Sensorless adaptive optics multimodal en-face small animal retinal imaging

DJ Wahl, R Ng, MJ Ju, Y Jian… - Biomedical Optics Express, 2018 - opg.optica.org
Vision researchers often use small animals due to the availability of many transgenic strains
that model human diseases or express biomarkers. Adaptive optics (AO) enables non …

Aberration measurement and correction on a large field of view in fluorescence microscopy

T Furieri, D Ancora, G Calisesi, S Morara… - Biomedical optics …, 2021 - opg.optica.org
The aberrations induced by the sample and/or by the sample holder limit the resolution of
optical microscopes. Wavefront correction can be achieved using a deformable mirror with …