Mechanisms of key innate immune cells in early-and late-onset preeclampsia

I Aneman, D Pienaar, S Suvakov, TP Simic… - Frontiers in …, 2020 - frontiersin.org
Preeclampsia is a complex cardiovascular disorder of pregnancy with underlying
multifactorial pathogeneses; however, its etiology is not fully understood. It is characterized …

Vascular adaptation in pregnancy and endothelial dysfunction in preeclampsia

DS Boeldt, IM Bird - The Journal of endocrinology, 2016 - pmc.ncbi.nlm.nih.gov
Maternal vascular adaptation to pregnancy is critically important in order to expand the
capacity for blood flow through the uteroplacental unit to meet the needs of the develo** …

[HTML][HTML] Preeclampsia: A review of the pathogenesis and possible management strategies based on its pathophysiological derangements

AAF El-Sayed - Taiwanese Journal of Obstetrics and Gynecology, 2017 - Elsevier
This review is divided into three parts. The first part briefly describes the pathogenesis of
preeclampsia. This is followed by reviewing previously reported management strategies of …

Maternal serum cytokine concentrations in healthy pregnancy and preeclampsia

T Spence, PJ Allsopp, AJ Yeates… - Journal of …, 2021 - Wiley Online Library
The maternal immune response is essential for successful pregnancy, promoting immune
tolerance to the fetus while maintaining innate and adaptive immunity. Uncontrolled …

Preeclampsia and cardiovascular risk for offspring

W Wojczakowski, Ż Kimber-Trojnar, F Dziwisz… - Journal of Clinical …, 2021 - mdpi.com
There is growing evidence of long-term cardiovascular sequelae in children after in utero
exposure to preeclampsia. Maternal hypertension and/or placental ischaemia during …

Effects of maternal obesity and gestational diabetes mellitus on the placenta: current knowledge and targets for therapeutic interventions

S Bedell, J Hutson, B de Vrijer… - Current vascular …, 2021 - ingentaconnect.com
Obesity and gestational diabetes mellitus (GDM) are becoming more common among
pregnant women worldwide and are individually associated with a number of placenta …

The role of miRNA-210 in pre-eclampsia development

I Jaszczuk, D Koczkodaj, A Kondracka… - Annals of …, 2022 - Taylor & Francis
MicroRNAs (miRNAs) are a class of small non-coding, single-stranded RNAs (ribonucleic
acids) that play important roles in many vital processes through their impact on gene …

The central role of natural killer cells in preeclampsia

X Wei, X Yang - Frontiers in Immunology, 2023 - frontiersin.org
Preeclampsia (PE) is a disease that is unique to pregnancy and affects multiple systems. It
can lead to maternal and perinatal mortality. The precise etiology of PE is unclear. Patients …

Vitamin D and inflammatory cytokines in healthy and preeclamptic pregnancies

D Barrera, L Díaz, N Noyola-Martínez, A Halhali - Nutrients, 2015 - mdpi.com
Preeclampsia is a pregnancy disease characterized by hypertension and proteinuria.
Among several disorders, the imbalance of inflammatory cytokines and the alteration of …

Biomarkers of oxidative stress in pregnancy complications

JSM Cuffe, ZC Xu, AV Perkins - Biomarkers in medicine, 2017 - Taylor & Francis
Pregnancy complications including pre-eclampsia, gestational-diabetes mellitus, preterm
birth and intrauterine growth restriction can cause acute and chronic health problems for the …