Using machine learning approaches for multi-omics data analysis: A review

PS Reel, S Reel, E Pearson, E Trucco… - Biotechnology advances, 2021 - Elsevier
With the development of modern high-throughput omic measurement platforms, it has
become essential for biomedical studies to undertake an integrative (combined) approach to …

Integrated multi-omics analyses in oncology: a review of machine learning methods and tools

G Nicora, F Vitali, A Dagliati, N Geifman… - Frontiers in …, 2020 - frontiersin.org
In recent years, high-throughput sequencing technologies provide unprecedented
opportunity to depict cancer samples at multiple molecular levels. The integration and …

Machine learning and clinical epigenetics: a review of challenges for diagnosis and classification

S Rauschert, K Raubenheimer, PE Melton… - Clinical epigenetics, 2020 - Springer
Background Machine learning is a sub-field of artificial intelligence, which utilises large data
sets to make predictions for future events. Although most algorithms used in machine …

Integrative methods for analyzing big data in precision medicine

V Gligorijević, N Malod‐Dognin, N Pržulj - Proteomics, 2016 - Wiley Online Library
We provide an overview of recent developments in big data analyses in the context of
precision medicine and health informatics. With the advance in technologies capturing …

Circulating cell-free DNA in breast cancer: size profiling, levels, and methylation patterns lead to prognostic and predictive classifiers

M Panagopoulou, M Karaglani, I Balgkouranidou… - Oncogene, 2019 - nature.com
Blood circulating cell-free DNA (ccfDNA) is a suggested biosource of valuable clinical
information for cancer, meeting the need for a minimally-invasive advancement in the route …

moBRCA-net: a breast cancer subtype classification framework based on multi-omics attention neural networks

JM Choi, H Chae - BMC bioinformatics, 2023 - Springer
Background Breast cancer is a highly heterogeneous disease that comprises multiple
biological components. Owing its diversity, patients have different prognostic outcomes; …

BCDForest: a boosting cascade deep forest model towards the classification of cancer subtypes based on gene expression data

Y Guo, S Liu, Z Li, X Shang - BMC bioinformatics, 2018 - Springer
Background The classification of cancer subtypes is of great importance to cancer disease
diagnosis and therapy. Many supervised learning approaches have been applied to cancer …

A comparative study of multi-omics integration tools for cancer driver gene identification and tumour subty**

A Sathyanarayanan, R Gupta… - Briefings in …, 2020 - academic.oup.com
Oncogenesis and cancer can arise as a consequence of a wide range of genomic
aberrations including mutations, copy number alterations, expression changes and …

NCG 5.0: updates of a manually curated repository of cancer genes and associated properties from cancer mutational screenings

O An, GM Dall'Olio, TP Mourikis… - Nucleic acids …, 2016 - academic.oup.com
Abstract The Network of Cancer Genes (NCG, http://ncg. kcl. ac. uk/) is a manually curated
repository of cancer genes derived from the scientific literature. Due to the increasing …

Machine learning analysis of TCGA cancer data

J Liñares-Blanco, A Pazos… - PeerJ Computer …, 2021 - peerj.com
In recent years, machine learning (ML) researchers have changed their focus towards
biological problems that are difficult to analyse with standard approaches. Large initiatives …