Most proteins in cells are composed of multiple folding units (or domains) to perform
complex functions in a cooperative manner. Relative to the rapid progress in single-domain …

OMA is an established resource to elucidate evolutionary relationships among genes from
currently 2326 genomes covering all domains of life. OMA provides pairwise and groupwise …

Abstract InterPro (http://www. ebi. ac. uk/interpro/) is a freely available database used to
classify protein sequences into families and to predict the presence of important domains …

The latest version of the CATH-Gene3D protein structure classification database has
recently been released (version 4.1, http://www. cathdb. info). The resource comprises over …

Abstract The Orthologous Matrix (OMA) is a leading resource to relate genes across many
species from all of life. In this update paper, we review the recent algorithmic improvements …

Tree peony (Paeonia ostii) is an economically important ornamental plant native to China. It
is also notable for its seed oil, which is abundant in unsaturated fatty acids such as α …

Computational modelling of proteins has been a major catalyst in structural biology.
Bioinformatics groups have exploited the repositories of known structures to predict high …

Functional annotation of protein sequence with high accuracy has become one of the most
important issues in modern biomedical studies, and computational approaches of …

Abstract Analysis of metagenomic and metatranscriptomic data is complicated and typically
requires extensive computational resources. Leveraging a curated reference database of …

Abstract Gene3D (http://gene3d. biochem. ucl. ac. uk) is a database of globular domain
annotations for millions of available protein sequences. Gene3D has previously featured in …