MYB transcription factors are highly conserved from plants to vertebrates, indicating that
their functions embrace fundamental mechanisms in the biology of cells and organisms. In …

The dimerization partner, RB-like, E2F and multi-vulval class B (DREAM) complex provides
a previously unsuspected unifying role in the cell cycle by directly linking p130, p107, E2F …

Angiocentric gliomas are pediatric low-grade gliomas (PLGGs) without known recurrent
genetic drivers. We performed genomic analysis of new and published data from 249 …

Glycogen synthase kinase‐3 (GSK‐3) is a protein‐serine kinase implicated in the hormonal
control of several regulatory proteins including glycogen synthase and the transcription …

The c-myb proto-oncogene encodes a sequence-specific DNA-binding protein. To better
understand its normal biological function, we have altered the c-myb gene by homologous …

The maize P gene, which specifies red pigmentation of the kernel pericarp, cob, and other
floral organs, has been an important model since the early days of modern genetics. Here …

The myb gene family consists of three members, named A, B and c-myb which encode
nuclear proteins that function as transcriptional transactivators. Proteins encoded by these …

The DNA-binding region of Myb consists of three imperfect tandem repeats (Rl, R2, and R3).
We have determined the solution structure of a specific DNA complex of the minimum DNA …

Primary gene induction or repression in eukaryotes does not require de novo protein
synthesis, suggesting the involvement of posttranslational modifications. Since many …

Excessive production of collagen type I is a major contributor to hepatic fibrosis. Activated
(myofibroblastic), but not quiescent, hepatic stellate cells (lipocytes) have a high level of …