Liver fibrosis refers to the process underlying the development of chronic liver diseases,
wherein liver cells are repeatedly destroyed and regenerated, which leads to an excessive …

Autoimmune hepatitis (AIH) is an autoimmune disease characterized by liver parenchymal
destruction and chronic fibrosis. Its exact etiology and pathogenesis are not yet fully …

The aryl hydrocarbon receptor (AhR) is a ubiquitously expressed ligand-activated
transcription factor. While initially identified as an environmental sensor, this receptor has …

Abstract The concanavalin A (Con A)-induced liver injury mouse model is a typical animal
model focusing on T cell-dependent hepatic damage in the field of autoimmune hepatitis …

Background and Aims Increasing evidence in recent years has suggested that microRNA‐7
(miR‐7) is an important gene implicated in the development of various diseases including …

Demethyleneberberine (DMB) is a natural product which has been reported to possess
mitochondria-targeting anti-oxidative and anti-inflammatory effect. However, the …

Autoimmune hepatitis (AIH) is a progressive hepatitis syndrome characterized by high
transaminase levels, interface hepatitis, hypergammaglobulinemia, and the presence of …

Hepatitis is characterized by elevated transaminase enzymes, programmed cell death, and
necrosis that lead to fibrosis and cirrhosis. Excessive immune stimulation plays a pivotal role …

The prevalence of immune-mediated liver diseases such as autoimmune liver disease or
viral hepatitis has increased in recent years, and the side effects of pre-existing treatments …

Autoimmune hepatitis (AIH) is a necroinflammatory disease associated with interactive cell
populations of the innate and adaptive immune systems. The contribution of conventional …