Prostate cancer has a long disease history and a wide variety and uncertainty in individual
patients' clinical progress. In recent years, we have seen a revolutionary advance in both …

Studies on familial aggregation of cancer may suggest an overall contribution of inherited
genes or a shared environment in the development of malignant disease. We performed a …

BACKGROUND Prostate cancer (PC) relative risks (RRs) are typically estimated based on
status of close relatives or presence of any affected relatives. This study provides RR …

Background The contribution of low-penetrant susceptibility variants to cancer is not clear.
With the aim of searching for genetic factors that contribute to cancer at one or more sites in …

Purpose: While the mitochondrion is known to be a key mediator of apoptosis, there has
been little inquiry into the inheritance pattern of mitochondria in patients with cancer. We …

Background Familial clustering of incident prostate cancer and some cancers at other
discordant sites has been reported. Less is known about familial clustering of fatal prostate …

In 2006 alone, nearly 234,460 men in the USA will be diagnosed with prostate cancer (PC).
In addition, about 27,000 will die from, rather than with, their disease (1). Although there is …

We analysed the relation between family history of cancer in first‐degree relatives and risk of
prostate cancer (PC) and benign prostatic hyperplasia (BPH) using data from a multicentric …

OBJECTIVES: The present study assessed more than 800 potential risk factors to identify
new predictors of breast cancer and compare the independence and relative importance of …

Family history of urogenital cancers has been associated with an increased risk of cancer at
the same sites. To evaluate the risks of bladder, prostate and renal cell neoplasms for family …