Optimal delivery of poorly soluble drugs using electrospun nanofiber technology: Challenges, state of the art, and future directions

S Pattnaik, K Swain… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Poor aqueous solubility of both, existing drug molecules and those which are currently in the
developmental stage, have posed a great challenge to pharmaceutical scientists because …

Curcumin, hemostasis, thrombosis, and coagulation

F Keihanian, A Saeidinia, RK Bagheri… - Journal of cellular …, 2018 - Wiley Online Library
Atherothrombotic cardiovascular disease is a major cause of mortality throughout the world.
Platelet activation and aggregation play a central role in hemostasis and thrombosis. Herbal …

[HTML][HTML] Relationships between mechanical properties and drug release from electrospun fibers of PCL and PLGA blends

SF Chou, KA Woodrow - Journal of the mechanical behavior of biomedical …, 2017 - Elsevier
Electrospun nanofibers have the potential to achieve high drug loading and the ability to
sustain drug release. Mechanical properties of the drug-incorporated fibers suggest the …

Curcumin-loaded electrospun PHBV nanofibers as potential wound-dressing material

G Mutlu, S Calamak, K Ulubayram, E Guven - Journal of Drug Delivery …, 2018 - Elsevier
Advances in nanotechnology have led to the generation of many new wound-dressing
materials with high surface area and high productivity at a low cost. The present study aims …

The effect of molecular weight and content of PEG on in vitro drug release of electrospun curcumin loaded PLA/PEG nanofibers

L Moradkhannejhad, M Abdouss, N Nikfarjam… - Journal of Drug Delivery …, 2020 - Elsevier
This study focused on preparation of curcumin (CUR) loaded poly (lactic acid)(PLA)
nanofibers by electrospinning technique. The hydrophilicity of nanofibers was modified by …

Accelerated Healing of Diabetic Wounds Treated with L-Glutamic acid Loaded Hydrogels Through Enhanced Collagen Deposition and Angiogenesis: An In Vivo …

P Thangavel, B Ramachandran, S Chakraborty… - Scientific reports, 2017 - nature.com
We have developed L-glutamic acid (LG) loaded chitosan (CS) hydrogels to treat diabetic
wounds. Although literature reports wound healing effects of poly (glutamic acid)-based …

Immobilization of bromelain and ZnO nanoparticles on silk fibroin nanofibers as an antibacterial and anti-inflammatory burn dressing

M Hasannasab, J Nourmohammadi… - International Journal of …, 2021 - Elsevier
Burns is a critical fatal event due to the risk of infection and complex inflammatory cascades.
This study aimed to fabricate and characterize a new antibacterial and anti-inflammatory …

Applications of electrospun nanofibers with antioxidant properties: A review

A Vilchez, F Acevedo, M Cea, M Seeger, R Navia - Nanomaterials, 2020 - mdpi.com
Antioxidants can be encapsulated to enhance their solubility or bioavailability or to protect
them from external factors. Electrospinning has proven to be an excellent option for …

Electrospun curcumin-loaded cellulose acetate/polyvinylpyrrolidone fibrous materials with complex architecture and antibacterial activity

PB Tsekova, MG Spasova, NE Manolova… - Materials Science and …, 2017 - Elsevier
Novel fibrous materials from cellulose acetate (CA) and polyvinylpyrrolidone (PVP)
containing curcumin (Curc) with original design were prepared by one-pot electrospinning …

An investigation of konjac glucomannan-keratin hydrogel scaffold loaded with Avena sativa extracts for diabetic wound healing

PK Veerasubramanian, P Thangavel, R Kannan… - Colloids and Surfaces B …, 2018 - Elsevier
We have developed a novel hydrogel composed of konjac glucomannan (KGM), human hair
proteins (KER), and an ethanolic extract of Avena sativa (OAT) and evaluated its potential as …