Multiplicity of cerebrospinal fluid functions: New challenges in health and disease

CE Johanson, JA Duncan, PM Klinge, T Brinker… - Cerebrospinal fluid …, 2008 - Springer
This review integrates eight aspects of cerebrospinal fluid (CSF) circulatory dynamics:
formation rate, pressure, flow, volume, turnover rate, composition, recycling and …

Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids

AN Cho, Y **, Y An, J Kim, YS Choi, JS Lee… - Nature …, 2021 - nature.com
Brain organoids derived from human pluripotent stem cells provide a highly valuable in vitro
model to recapitulate human brain development and neurological diseases. However, the …

Exosomes as novel regulators of adult neurogenic niches

LF Bátiz, MA Castro, PV Burgos… - Frontiers in cellular …, 2016 - frontiersin.org
Adult neurogenesis has been convincingly demonstrated in two regions of the mammalian
brain: the sub-granular zone (SGZ) of the dentate gyrus (DG) in the hippocampus, and the …

Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia

B Guirao, A Meunier, S Mortaud, A Aguilar… - Nature cell …, 2010 - nature.com
In mammals, motile cilia cover many organs, such as fallopian tubes, respiratory tracts and
brain ventricles. The development and function of these organs critically depend on efficient …

Engineering stem cell-derived 3D brain organoids in a perfusable organ-on-a-chip system

Y Wang, L Wang, Y Guo, Y Zhu, J Qin - RSC advances, 2018 - pubs.rsc.org
Brain organoids derived from the self-organization of human induced pluripotent stem cells
(hiPSCs) represent a new class of in vitro organ system for modeling brain development and …

A controllable perfusion microfluidic chip for facilitating the development of retinal ganglion cells in human retinal organoids

J Gong, Y Gong, T Zou, Y Zeng, C Yang, L Mo, J Kang… - Lab on a Chip, 2023 - pubs.rsc.org
Retinal organoids (ROs) derived from human pluripotent stem cells (hPSCs) have become a
promising model in vitro to recapitulate human retinal development, which can be further …

From the Golgi–Cajal map** to the transmitter-based characterization of the neuronal networks leading to two modes of brain communication: wiring and volume …

K Fuxe, A Dahlström, M Höistad, D Marcellino… - Brain research …, 2007 - Elsevier
After Golgi–Cajal mapped neural circuits, the discovery and map** of the central
monoamine neurons opened up for a new understanding of interneuronal communication …

Neural defects and cardiac arrhythmia in fish larvae following embryonic exposure to 2, 2′, 4, 4′-tetrabromodiphenyl ether (PBDE 47)

SC Lema, IR Schultz, NL Scholz, JP Incardona… - Aquatic toxicology, 2007 - Elsevier
Polybrominated diphenyl ethers (PBDEs) are added to plastics, polyurethane foam, and
textiles as a flame retardant. While PBDEs play a key role in reducing loss of human life and …

Loss of Dishevelleds disrupts planar polarity in ependymal motile cilia and results in hydrocephalus

S Ohata, J Nakatani, V Herranz-Pérez, JG Cheng… - Neuron, 2014 - cell.com
Defects in ependymal (E) cells, which line the ventricle and generate cerebrospinal fluid flow
through ciliary beating, can cause hydrocephalus. Dishevelled genes (Dvls) are essential for …

The choroid plexus in the rise, fall and repair of the brain

DF Emerich, SJM Skinner, CV Borlongan… - …, 2005 - Wiley Online Library
The choroid plexuses (CPs) are involved in the most‐basic aspects of neural function
including maintaining the extracellular milieu of the brain by actively modulating chemical …