Vaccines based on historical virus isolates provide limited protection from continuously
evolving RNA viruses, such as influenza viruses or coronaviruses, which occasionally spill …

It has been more than three years since the first emergence of coronavirus disease 2019
(COVID-19) and millions of lives have been taken to date. Like most pandemics caused by …

The continuing emergence of SARS-CoV-2 variants highlights the need to update COVID-19
vaccine compositions. However, immune imprinting induced by vaccination based on the …

SARS-CoV-2 subvariants BQ. 1.1 and XBB. 1 have been circulating globally with superior
growth advantages over most omicron mutants (appendix p 5). However, XBB. 1.5, a …

Convergent evolution of SARS-CoV-2 Omicron BA. 2, BA. 4, and BA. 5 lineages has led to
the emergence of several new subvariants, including BA. 2.75. 2, BA. 4.6. and BQ. 1.1. The …

Omicron subvariants continuingly challenge current vaccination strategies. Here, we
demonstrate nearly complete escape of the XBB. 1.5, CH. 1.1, and CA. 3.1 variants from …

The protective efficacy of serum antibodies results from the interplay of antigen-specific B
cell clones of different affinities and specificities. These cellular dynamics underlie serum …

Evolution of SARS-CoV-2 requires the reassessment of current vaccine measures. Here, we
characterized BA. 2.86 and XBB-derived variant FLip by investigating their neutralization …

Correspondence 280 www. thelancet. com/infection Vol 23 March 2023 resistant to BA. 2
breakthrough infection sera (41-fold versus B. 1· 1, 20-fold versus BA. 2) and BA. 5 …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) XBB lineages have
achieved dominance worldwide and keep on evolving. Convergent evolution of XBB …