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Drug-induced liver injury
Drug-induced liver injury (DILI) is an adverse reaction to drugs or other xenobiotics that
occurs either as a predictable event when an individual is exposed to toxic doses of some …
occurs either as a predictable event when an individual is exposed to toxic doses of some …
Burden of liver diseases in the world
Liver disease accounts for approximately 2 million deaths per year worldwide, 1 million due
to complications of cirrhosis and 1 million due to viral hepatitis and hepatocellular …
to complications of cirrhosis and 1 million due to viral hepatitis and hepatocellular …
Astaxanthin activated the Nrf2/HO-1 pathway to enhance autophagy and inhibit ferroptosis, ameliorating acetaminophen-induced liver injury
X Cai, S Hua, J Deng, Z Du, D Zhang… - … applied materials & …, 2022 - ACS Publications
Acetaminophen (APAP)-induced liver injury (AILI) is a common liver disease in clinical
practice. Only one clinically approved drug, N-acetylcysteine (NAC), for the treatment of AILI …
practice. Only one clinically approved drug, N-acetylcysteine (NAC), for the treatment of AILI …
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
There are currently more than 1000 prescription medications available for use in the United
States and more than 100,000 over-the-counter herbal and dietary supplements (HDS) …
States and more than 100,000 over-the-counter herbal and dietary supplements (HDS) …
Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice
Acetaminophen (APAP) overdose is a leading cause of drug-induced liver injury (DILI). The
impact of the gut microbiota and associated metabolites on APAP and liver function remains …
impact of the gut microbiota and associated metabolites on APAP and liver function remains …
Role of liver sinusoidal endothelial cells in liver diseases
J Gracia-Sancho, E Caparrós… - Nature reviews …, 2021 - nature.com
Liver sinusoidal endothelial cells (LSECs) form the wall of the hepatic sinusoids. Unlike
other capillaries, they lack an organized basement membrane and have cytoplasm that is …
other capillaries, they lack an organized basement membrane and have cytoplasm that is …
Artificial liver support in patients with liver failure: a modified DELPHI consensus of international experts
F Saliba, R Bañares, FS Larsen, A Wilmer… - Intensive Care …, 2022 - Springer
The present narrative review on albumin dialysis provides evidence-based and expert
opinion guidelines for clinicians caring for adult patients with different types of liver failure …
opinion guidelines for clinicians caring for adult patients with different types of liver failure …
Acetaminophen (APAP) hepatotoxicity—isn't it time for APAP to go away?
WM Lee - Journal of hepatology, 2017 - Elsevier
Acetaminophen (APAP) is the most commonly used drug for the treatment of pain and fever
around the world. At the same time, APAP can cause dose-related hepatocellular necrosis …
around the world. At the same time, APAP can cause dose-related hepatocellular necrosis …
Hepatic encephalopathy
EFM Wijdicks - New England Journal of Medicine, 2016 - Mass Medical Soc
Hepatic Encephalopathy | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …
Management of acute liver failure: update 2022
S Tujios, RT Stravitz, WM Lee - Seminars in liver disease, 2022 - thieme-connect.com
Abbreviated pathogenesis and clinical course of the acute liver failure syndrome. The
pathogenesis and clinical course of the syndrome of acute liver failure (ALF) differs …
pathogenesis and clinical course of the syndrome of acute liver failure (ALF) differs …