A systems biology view of blood vessel growth and remodelling

EA Logsdon, SD Finley, AS Popel… - Journal of cellular and …, 2014 - Wiley Online Library
Blood travels throughout the body in an extensive network of vessels–arteries, veins and
capillaries. This vascular network is not static, but instead dynamically remodels in response …

Multiscale computational models of complex biological systems

J Walpole, JA Papin, SM Peirce - Annual review of biomedical …, 2013 - annualreviews.org
Integration of data across spatial, temporal, and functional scales is a primary focus of
biomedical engineering efforts. The advent of powerful computing platforms, coupled with …

The effect of vascular endothelial growth factor (VEGF) presentation within fibrin matrices on endothelial cell branching

SM Anderson, SN Siegman, T Segura - Biomaterials, 2011 - Elsevier
Vascular endothelial growth factor (VEGF) has been extensively investigated to promote
vascularization at damaged or diseased sites and in tissue implants. Here we are interested …

Understanding the biology of reactive oxygen species and their link to cancer: NADPH oxidases as novel pharmacological targets

IP Harrison, S Selemidis - Clinical and Experimental …, 2014 - Wiley Online Library
Reactive oxygen species (ROS), the cellular products of myriad physiological processes,
have long been understood to lead to cellular damage if produced in excess and to be a …

Agent-based model of angiogenesis simulates capillary sprout initiation in multicellular networks

J Walpole, JC Chappell, JG Cluceru… - Integrative …, 2015 - academic.oup.com
Many biological processes are controlled by both deterministic and stochastic influences.
However, efforts to model these systems often rely on either purely stochastic or purely rule …

Modeling Human Epiblast Morphogenesis

A Resto - 2023 - deepblue.lib.umich.edu
The development of the human embryo is arguably the most complex process that we could
care to study. In this process, the develo** embryo must undergo proliferation …

A dynamical model of apoptosis and its role in tumor progression

P Laise, D Fanelli, A Arcangeli - Communications in Nonlinear Science and …, 2012 - Elsevier
Apoptosis is a biological process crucial for the development and maintenance of healthy
living organism. A deregulated apoptosis underlies many diseases, including cancer. Under …

Biyokimyasal Reaksiyon Sistemlerinin Modellenmesi için Deterministik ve Stokastik Yaklaşım

B Oğraş, D Altıntan - Selçuk Üniversitesi Fen Fakültesi Fen Dergisi, 2021 - dergipark.org.tr
Biyokimyasal süreçler, birbirleriyle, farklı reaksiyon kanallarıyla etkileşime giren türleri içeren
reaksiyon ağları olarak düşünülebilirler. Deterministik yaklaşım ve stokastik yaklaşım bu …

[PDF][PDF] Joseph Walpole

S Peirce-Cottler - 2015 - scholar.archive.org
Biological systems are inherently complex in nature; they are comprised of multiple
functional networks that operate across diverse temporal and spatial domains to sustain an …

[BOOK][B] Vascular Endothelial Growth Factor (VEGF) Presentation Modulates Human Umbilical Vein Endothelial Cell (HUVEC) Signaling and Tube Morphology

SM Anderson - 2011 - search.proquest.com
Application of regenerative medicine technology is hindered by lack of biomaterials capable
of inducing perfusion after implantation. The most successful tissue engineering products to …