Metabolic engineering aims to develop efficient cell factories by rewiring cellular
metabolism. As one of the most commonly used cell factories, Saccharomyces cerevisiae …

Microbial bioproduction of chemicals, proteins, and primary metabolites from cheap carbon
sources is currently an advancing area in industrial research. The model yeast …

Development of high throughput analytical methods has given physicians the potential
access to extensive and patient-specific data sets, such as gene sequences, gene …

An increasing number of industrial bioprocesses capitalize on living cells by using them as
cell factories that convert sugars into chemicals. These processes range from the production …

The genome‐scale model (GEM) of metabolism in the bacterium Escherichia coli K‐12 has
been in development for over a decade and is now in wide use. GEM‐enabled studies of E …

Production of recombinant proteins for use as pharmaceuticals, so-called
biopharmaceuticals, is a multi-billion dollar industry. Many different cell factories are used for …

Yeast Saccharomyces cerevisiae is an important industrial host for production of enzymes,
pharmaceutical and nutraceutical ingredients and recently also commodity chemicals and …

The production of recombinant therapeutic proteins is one of the fast-growing areas of
molecular medicine and currently plays an important role in treatment of several diseases …

The construction of high-performance microbial cell factories (MCFs) is the centerpiece of
biomanufacturing. However, the complex metabolic regulatory network of microorganisms …

Yeasts have been widely used for production of bread, beer and wine, as well as for
production of bioethanol, but they have also been designed as cell factories to produce …