Initiating pollen sensitization–complex source, complex mechanisms

L Pointner, A Bethanis, M Thaler… - Clinical and translational …, 2020 - Springer
The mechanisms involved in the induction of allergic sensitization by pollen are not fully
understood. Within the last few decades, findings from epidemiological and experimental …

Tolerance mechanisms in allergen immunotherapy

ZC Sözener, D Mungan, L Cevhertas… - Current opinion in …, 2020 - journals.lww.com
Tolerance mechanisms in allergen immunotherapy : Current Opinion in Allergy and Clinical
Immunology Tolerance mechanisms in allergen immunotherapy : Current Opinion in Allergy …

Mechanisms and biomarkers of successful allergen-specific immunotherapy

JF López, MB Imam, P Satitsuksanoa, S Lems… - Asia Pacific …, 2022 - journals.lww.com
Allergen-specific immunotherapy (AIT) is considered the only curative treatment for allergic
diseases mediated by immunoglobulin E (IgE). Currently, the route of administration …

Supramolecular Motion Enables Chondrogenic Bioactivity of a Cyclic Peptide Mimetic of Transforming Growth Factor-β1

SC Yuan, Z Álvarez, SR Lee, RZ Pavlović… - Journal of the …, 2024 - ACS Publications
Transforming growth factor (TGF)-β1 is a multifunctional protein that is essential in many
cellular processes that include fibrosis, inflammation, chondrogenesis, and cartilage repair …

Human bone marrow-derived mesenchymal stromal cells cultured in serum-free media demonstrate enhanced antifibrotic abilities via prolonged survival and robust …

S Takao, T Nakashima, T Masuda, M Namba… - Stem Cell Research & …, 2021 - Springer
Abstract Background Mesenchymal stromal cells (MSCs) are a potential therapeutic tool for
pulmonary fibrosis. However, ex vivo MSC expansion using serum poses risks of harmful …

How do pollen allergens sensitize?

SV Guryanova, EI Finkina, DN Melnikova… - Frontiers in Molecular …, 2022 - frontiersin.org
Plant pollen is one of the main sources of allergens causing allergic diseases such as
allergic rhinitis and asthma. Several allergens in plant pollen are panallergens which are …

[HTML][HTML] Antarctic krill antioxidant peptides show inferior IgE-binding ability and RBL-2H3 cell degranulation

J Ding, C Zhu, P Jiang, L Qi, N Sun, S Lin - Food Science and Human …, 2023 - Elsevier
Enzymatic hydrolysis, isolation, and purification might make a great deal of difference in
antioxidant activity and antigenicity of peptide components. This study aimed to isolate and …

What inhalant allergens can do and not do?—The cooperation of allergens and their source in Th2 polarization and allergic sensitization

S Grosse-Kathoefer, L Aglas, F Ferreira… - Allergo Journal …, 2023 - Springer
Inhalant allergens are the most common triggers of allergy-related respiratory symptoms [1]
and represent a global health problem. Approximately 400 million people globally suffer …

Reducing the allergenicity of pea protein based on the enzyme action of alcalase

J Ding, H Ju, L Zhong, L Qi, N Sun, S Lin - Food & Function, 2021 - pubs.rsc.org
Enzymatic hydrolysis could be one of the crucial means to limit the allergenicity of allergens.
The allergenicity of pea peptides was evaluated using indirect ELISA and RBL-2H3 cell …

When the allergy alarm bells toll: The role of Toll-like receptors in allergic diseases and treatment

M Wenger, S Grosse-Kathoefer, A Kraiem… - Frontiers in Molecular …, 2023 - frontiersin.org
Toll-like receptors of the human immune system are specialized pathogen detectors able to
link innate and adaptive immune responses. TLR ligands include among others bacteria …