Polycystic ovary syndrome: etiology, current management, and future therapeutics

S Singh, N Pal, S Shubham, DK Sarma… - Journal of Clinical …, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder, typically
characterized by anovulation, infertility, obesity, insulin resistance, and polycystic ovaries …

Endocrine-disrupting chemicals: implications for human health

LG Kahn, C Philippat, SF Nakayama… - The lancet Diabetes & …, 2020 - thelancet.com
Since reports published in 2015 and 2016 identified 15 probable exposure–outcome
associations, there has been an increase in studies in humans of exposure to endocrine …

Sex hormone signaling and regulation of immune function

JP Hoffmann, JA Liu, K Seddu, SL Klein - Immunity, 2023 - cell.com
Immune responses to antigens, including innocuous, self, tumor, microbial, and vaccine
antigens, differ between males and females. The quest to uncover the mechanisms for …

Re‐evaluation of the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs

EFSA Panel on Food Contact Materials … - EFSA …, 2023 - Wiley Online Library
In 2015, EFSA established a temporary tolerable daily intake (t‐TDI) for BPA of 4 μg/kg body
weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the …

Endocrine disruptors in water and their effects on the reproductive system

A Gonsioroski, VE Mourikes, JA Flaws - International journal of molecular …, 2020 - mdpi.com
Anthropogenic contaminants in water can impose risks to reproductive health. Most of these
compounds are known to be endocrine disrupting chemicals (EDCs). EDCs can impact the …

Challenges of plastic waste generation and management in sub-Saharan Africa: A review

OO Ayeleru, S Dlova, OJ Akinribide, F Ntuli… - Waste Management, 2020 - Elsevier
Recently, the issues of land-based plastics and their associated challenges in the marine
world have been widely publicised in the media and scientific literature. Thus far, despite …

A comprehensive review on the carcinogenic potential of bisphenol A: clues and evidence

NG Khan, J Correia, D Adiga, PS Rai… - … Science and Pollution …, 2021 - Springer
Abstract Bisphenol A [BPA;(CH 3) 2 C (C 6 H 4 OH) 2] is a synthetic chemical used as a
precursor material for the manufacturing of plastics and resins. It gained attention due to its …

Endocrine disrupting chemicals in polycystic ovary syndrome: the relevant role of the theca and granulosa cells in the pathogenesis of the ovarian dysfunction

M Jozkowiak, H Piotrowska-Kempisty, D Kobylarek… - Cells, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common heterogeneous endocrine disorder
among women of reproductive age. The pathogenesis of PCOS remains elusive; however …

Endocrine disrupting chemical Bisphenol A and its potential effects on female health

IA Kawa, Q Fatima, SA Mir, H Jeelani… - Diabetes & Metabolic …, 2021 - Elsevier
Background and aim A large number of chemical compounds with endocrine-disrupting
activity have been documented. These chemicals are ubiquitous and widely used in many …

[HTML][HTML] Exposure to bisphenol A and its analogs and polycystic ovarian syndrome in women of childbearing age: A multicenter case-control study

W Zhan, W Tang, X Shen, H Xu, J Zhang - Chemosphere, 2023 - Elsevier
Background/objectives In recent years, the reproductive toxicity of new bisphenol analogs
has garnered much interest, but it remains to be determined whether bisphenol analogs …