Optimizing the outcomes of pancreatic cancer surgery

O Strobel, J Neoptolemos, D Jaeger… - Nature reviews Clinical …, 2019‏ - nature.com
Pancreatic cancer is likely to become the second most frequent cause of cancer-associated
mortality within the next decade. Surgical resection with adjuvant systemic chemotherapy …

Improvement of surgical results for pancreatic cancer

W Hartwig, J Werner, D Jäger, J Debus… - The Lancet …, 2013‏ - thelancet.com
Surgery is the only potential hope of cure for patients with pancreatic cancer. Advantageous
tumour characteristics and complete tumour resection are the factors most relevant for a …

Systematic review and meta-analysis of the volume–outcome relationship in pancreatic surgery

GA Gooiker, W Van Gijn, M Wouters… - Journal of British …, 2011‏ - academic.oup.com
Background Many studies have shown lower mortality and higher survival rates after
pancreatic surgery with high-volume providers, suggesting that centralization of pancreatic …

Understanding the volume-outcome effect in cardiovascular surgery: the role of failure to rescue

AA Gonzalez, JB Dimick, JD Birkmeyer… - JAMA …, 2014‏ - jamanetwork.com
Importance To effectively guide interventions aimed at reducing mortality in low-volume
hospitals, the underlying mechanisms of the volume-outcome relationship must be further …

Impact of hospital volume on hospital mortality, length of stay and total costs after pancreaticoduodenectomy

R Yoshioka, H Yasunaga, K Hasegawa… - Journal of British …, 2014‏ - academic.oup.com
Background High morbidity and mortality rates after pancreaticoduodenectomy (PD) have
led to concentration of this surgery in high-volume centres, with improved outcomes. The …

The volume-outcome relationship in critical care

YL Nguyen, DJ Wallace, Y Yordanov, L Trinquart… - Chest, 2015‏ - Elsevier
OBJECTIVE The purpose of this study was to systematically review the research on volume
and outcome relationships in critical care. METHODS From January 1, 2001, to April 30 …

[HTML][HTML] Curing pancreatic cancer

B Traub, KH Link, M Kornmann - Seminars in cancer biology, 2021‏ - Elsevier
The distinct biology of pancreatic cancer with aggressive and early invasive tumor cells, a
tumor promoting microenvironment, late diagnosis, and high therapy resistance poses major …

Impact of sarcopenic obesity on failure to rescue from major complications following pancreaticoduodenectomy for cancer: results from a multicenter study

N Pecorelli, G Capretti, M Sandini, A Damascelli… - Annals of surgical …, 2018‏ - Springer
Background Failure to rescue (FTR) is a quality-of-care indicator in pancreatic surgery, but
may also identify patients who may not tolerate major postoperative complications despite …

Why do high-volume hospitals achieve better outcomes? A systematic review about intermediate factors in volume–outcome relationships

R Mesman, GP Westert, BJMM Berden, MJ Faber - Health Policy, 2015‏ - Elsevier
Objective To assess the role of process and structural factors in volume–outcome
relationships. Data sources Pubmed electronic database, until March 2014. Study design …

Comparison of rates and outcomes of readmission to index vs nonindex hospitals after major cancer surgery

SN Zafar, AA Shah, H Channa, M Raoof, L Wilson… - JAMA …, 2018‏ - jamanetwork.com
Importance Increasing regionalization of cancer surgery has the inadvertent potential to lead
to fragmentation of care if readmissions occur at a facility other than the index hospital. The …