High-throughput glycomic methods

I Trbojević-Akmačić… - Chemical …, 2022 - ACS Publications
Glycomics aims to identify the structure and function of the glycome, the complete set of
oligosaccharides (glycans), produced in a given cell or organism, as well as to identify …

Structure and function of non-digestible carbohydrates in the gut microbiome

RA Rastall, M Diez-Municio… - Beneficial …, 2022 - wageningenacademic.com
Together with proteins and fats, carbohydrates are one of the macronutrients in the human
diet. Digestible carbohydrates, such as starch, starch-based products, sucrose, lactose …

Changes in HMO concentrations throughout lactation: influencing factors, health effects and opportunities

C Thum, CR Wall, GA Weiss, W Wang, IMY Szeto… - Nutrients, 2021 - mdpi.com
Human milk oligosaccharides (HMOs) are important functional biomolecules in human
breast milk. Understanding the factors influencing differences in HMO composition and …

Advances and challenges for obtaining human milk oligosaccharides: Extraction from natural sources and synthesis by intentional design

J Gan, C Cao, B Stahl, X Zhao, J Yan - Trends in Food Science & …, 2023 - Elsevier
Abstract Background Human milk oligosaccharides (HMOs) are a group of structurally
diverse unconjugated carbohydrates that are bioactive and functional beyond their important …

Toward sequencing the human milk glycome: high-resolution cyclic ion mobility separations of core human milk oligosaccharide building blocks

TL Peterson, G Nagy - Analytical chemistry, 2021 - ACS Publications
Human milk oligosaccharides (HMOs) are an unconjugated class of glycans that have been
implicated for their role in promoting the healthy development of the brain–gut axes of …

Systematic Characterization of the Oligosaccharide Profile of Human Milk in Rural Areas of Central China: Quantitative Tracking of Human Milk Oligosaccharide …

L Zhu, X Peng, H Li, T Luo, J Wang, Y Gao… - Journal of Agricultural …, 2024 - ACS Publications
This study investigates changes in human milk oligosaccharide (HMO) composition over a
12 month breastfeeding period in rural central China. The HMO profiles of 97 mothers were …

Recent Advances on Lacto-N-neotetraose, a Commercially Added Human Milk Oligosaccharide in Infant Formula

P Zhang, Y Zhu, Z Li, W Zhang… - Journal of Agricultural and …, 2022 - ACS Publications
Human milk oligosaccharides (HMOs) act as the important prebiotics and display many
unique health effects for infants. Lacto-N-neotetraose (LNnT), an abundant HMO, attracts …

Comparison of twelve human milk oligosaccharides in mature milk from different areas in China in the Chinese Human Milk Project (CHMP) study

W Zhang, J Vervoort, J Pan, P Gao, H Zhu, X Wang… - Food Chemistry, 2022 - Elsevier
Human milk oligosaccharides (HMOs) act as a vital role in the development of infant's gut
microbiome and immune function. This study aimed to measure 12 oligosaccharides in milk …

Validated Multimethod Approach for Full Characterization of 2′-Fucosyl-d-lactose as an Industrially Produced Human Milk Oligosaccharide

V Neu, W Hoffmann, TD Weiß, M Puhl… - Analytical …, 2024 - ACS Publications
Human milk oligosaccharides are of high interest as active ingredients in infant formulas and
dietary food supplements. Full characterization of members of this compound class is …

Microbial production of human milk oligosaccharides

DSK Palur, SR Pressley, S Atsumi - Molecules, 2023 - mdpi.com
Human milk oligosaccharides (HMOs) are complex nonnutritive sugars present in human
milk. These sugars possess prebiotic, immunomodulatory, and antagonistic properties …