A guide to the Michaelis–Menten equation: steady state and beyond

B Srinivasan - The FEBS journal, 2022 - Wiley Online Library
The modern definition of enzymology is synonymous with the Michaelis–Menten equation
instituted by Leonor Michaelis and Maud Menten. Most textbooks, or chapters within …

Manganese compounds as water-oxidizing catalysts: from the natural water-oxidizing complex to nanosized manganese oxide structures

MM Najafpour, G Renger, M Hołynska… - Chemical …, 2016 - ACS Publications
All cyanobacteria, algae, and plants use a similar water-oxidizing catalyst for water
oxidation. This catalyst is housed in Photosystem II, a membrane-protein complex that …

Proton-coupled electron transfer guidelines, fair and square

R Tyburski, T Liu, SD Glover… - Journal of the American …, 2021 - ACS Publications
Proton-coupled electron transfer (PCET) reactions are fundamental to energy transformation
reactions in natural and artificial systems and are increasingly recognized in areas such as …

Frontiers, Opportunities, and Challenges in Biochemical and Chemical Catalysis of CO2 Fixation

AM Appel, JE Bercaw, AB Bocarsly, H Dobbek… - Chemical …, 2013 - ACS Publications
Two major energy-related problems confront the world in the next 50 years. First, increased
worldwide competition for gradually depleting fossil fuel reserves (derived from past …

Combined quantum mechanics/molecular mechanics (QM/MM) methods in computational enzymology

MW Van Der Kamp, AJ Mulholland - Biochemistry, 2013 - ACS Publications
Computational enzymology is a rapidly maturing field that is increasingly integral to
understanding mechanisms of enzyme-catalyzed reactions and their practical applications …

On the temperature dependence of enzyme-catalyzed rates

VL Arcus, EJ Prentice, JK Hobbs, AJ Mulholland… - Biochemistry, 2016 - ACS Publications
One of the critical variables that determine the rate of any reaction is temperature. For
biological systems, the effects of temperature are convoluted with myriad (and often …

Optomechanical detection of vibration modes of a single bacterium

E Gil-Santos, JJ Ruz, O Malvar, I Favero… - Nature …, 2020 - nature.com
Low-frequency vibration modes of biological particles, such as proteins, viruses and
bacteria, involve coherent collective vibrations at frequencies in the terahertz and gigahertz …

Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently

A Currin, N Swainston, PJ Day, DB Kell - Chemical Society Reviews, 2015 - pubs.rsc.org
The amino acid sequence of a protein affects both its structure and its function. Thus, the
ability to modify the sequence, and hence the structure and activity, of individual proteins in …

Proton transfer through the water gossamer

A Hassanali, F Giberti, J Cuny, TD Kühne… - Proceedings of the …, 2013 - pnas.org
The diffusion of protons through water is understood within the framework of the Grotthuss
mechanism, which requires that they undergo structural diffusion in a stepwise manner …

Hydrogen tunneling links protein dynamics to enzyme catalysis

JP Klinman, A Kohen - Annual review of biochemistry, 2013 - annualreviews.org
The relationship between protein dynamics and function is a subject of considerable
contemporary interest. Although protein motions are frequently observed during ligand …