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Imagining the future of optical microscopy: everything, everywhere, all at once
The optical microscope has revolutionized biology since at least the 17th Century. Since
then, it has progressed from a largely observational tool to a powerful bioanalytical platform …
then, it has progressed from a largely observational tool to a powerful bioanalytical platform …
More than double the fun with two-photon excitation microscopy
For generations researchers have been observing the dynamic processes of life through the
lens of a microscope. This has offered tremendous insights into biological phenomena that …
lens of a microscope. This has offered tremendous insights into biological phenomena that …
Deep tissue multi-photon imaging using adaptive optics with direct focus sensing and sha**
High-resolution optical imaging deep in tissues is challenging because of optical
aberrations and scattering of light caused by the complex structure of living matter. Here we …
aberrations and scattering of light caused by the complex structure of living matter. Here we …
Adaptive optics for optical microscopy
Optical microscopy is widely used to visualize fine structures. When applied to bioimaging,
its performance is often degraded by sample-induced aberrations. In recent years, adaptive …
its performance is often degraded by sample-induced aberrations. In recent years, adaptive …
Speed scaling in multiphoton fluorescence microscopy
After over 30 years of advances, multiphoton microscopy (MPM) is now instrumental in a
wide range of in vivo biological imaging applications. However, it has, until recently …
wide range of in vivo biological imaging applications. However, it has, until recently …
Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus
Hippocampal synaptic plasticity is important for learning and memory formation.
Homeostatic synaptic plasticity is a specific form of synaptic plasticity that is induced upon …
Homeostatic synaptic plasticity is a specific form of synaptic plasticity that is induced upon …
Second Near‐Infrared (NIR‐II) Window for Imaging‐Navigated Modulation of Brain Structure and Function
For a long time, optical imaging of the deep brain with high resolution has been a challenge.
Recently, with the advance in second near‐infrared (NIR‐II) bioimaging techniques and …
Recently, with the advance in second near‐infrared (NIR‐II) bioimaging techniques and …
Construction and use of an adaptive optics two-photon microscope with direct wavefront sensing
Two-photon microscopy, combined with the appropriate optical labelling, enables the
measurement and tracking of submicrometer structures within brain cells, as well as the …
measurement and tracking of submicrometer structures within brain cells, as well as the …
Miniature two-photon microscopic imaging using dielectric metalens
Miniature two-photon microscopy has emerged as a powerful technique for investigating
brain activity in freely moving animals. Ongoing research objectives include reducing probe …
brain activity in freely moving animals. Ongoing research objectives include reducing probe …
Label-free metabolic and structural profiling of dynamic biological samples using multimodal optical microscopy with sensorless adaptive optics
Label-free optical microscopy has matured as a noninvasive tool for biological imaging; yet,
it is criticized for its lack of specificity, slow acquisition and processing times, and weak and …
it is criticized for its lack of specificity, slow acquisition and processing times, and weak and …