Emerging nanomedicine approaches fighting tumor metastasis: animal models, metastasis-targeted drug delivery, phototherapy, and immunotherapy

C Liang, L Xu, G Song, Z Liu - Chemical Society Reviews, 2016 - pubs.rsc.org
Metastasis is directly or indirectly responsible for the majority of cancer deaths. Anti-
metastasis treatment is thus the key to cure cancer. Recent development in nanomedicine …

Bioinspired and biomimetic micro-and nanostructures in biomedicine

AP Johnson, C Sabu, KP Nivitha, R Sankar… - Journal of Controlled …, 2022 - Elsevier
Bioinspired and biomimetic micro-and nanostructures have a high significance in the field of
biomedicine. In this review, the possible applications of these micro-and nanostructures that …

[HTML][HTML] Biophysical regulation of cell behavior—cross talk between substrate stiffness and nanotopography

Y Yang, K Wang, X Gu, KW Leong - Engineering, 2017 - Elsevier
The stiffness and nanotopographical characteristics of the extracellular matrix (ECM)
influence numerous developmental, physiological, and pathological processes in vivo …

Highly efficient capture of circulating tumor cells by using nanostructured silicon substrates with integrated chaotic micromixers

S Wang, K Liu, J Liu, ZTF Yu, X Xu, L Zhao… - Angewandte …, 2011 - Wiley Online Library
Metastases are the most common cause of cancer-related death in patients with solid
tumors.[1–4] A considerable body of evidence indicates that tumor cells are shed from a …

Nanosized hydroxyapatite and other calcium phosphates: chemistry of formation and application as drug and gene delivery agents

V Uskoković, DP Uskoković - Journal of biomedical materials …, 2011 - Wiley Online Library
The first part of this review looks at the fundamental properties of hydroxyapatite (HAP), the
basic mineral constituent of mammalian hard tissues, including the physicochemical …

Semiconductor nanowire fabrication by bottom-up and top-down paradigms

RG Hobbs, N Petkov, JD Holmes - Chemistry of Materials, 2012 - ACS Publications
Semiconductor nanowires have been the subject of intensive research investment over the
past few decades. Their physical properties afford them applications in a vast network of …

Recent progress in inorganic and composite coatings with bactericidal capability for orthopaedic applications

A Simchi, E Tamjid, F Pishbin, AR Boccaccini - … , Biology and Medicine, 2011 - Elsevier
This review covers the most recent developments of inorganic and organic-inorganic
composite coatings for orthopedic implants, providing the interface with living tissue and with …

[HTML][HTML] Three-dimensional nanostructured substrates toward efficient capture of circulating tumor cells

S Wang, H Wang, J Jiao, KJ Chen… - … (International ed. in …, 2009 - ncbi.nlm.nih.gov
During the progression of metastasis, cancer cells detach from the solid primary tumor, enter
the blood stream, and travel to different tissues of the body. These breakaway cancer cells in …

Mucus as a barrier to lipophilic drugs

HH Sigurdsson, J Kirch, CM Lehr - International journal of pharmaceutics, 2013 - Elsevier
Mucus is a complex hydrogel, comprising glycoproteins, lipids, salts, DNA, enzymes and
cellular debris, covering many epithelial surfaces in the human body. Once secreted, mucin …

Specific capture and release of circulating tumor cells using aptamer‐modified nanosubstrates

Q Shen, L Xu, L Zhao, D Wu, Y Fan, Y Zhou… - Advanced …, 2013 - Wiley Online Library
Circulating tumor cells (CTCs)[1] are cancer cells that have propagated from tumors,
spreading into the bloodstream as the cellular origin of fatal metastasis. Besides …