Closed-loop vagus nerve stimulation for the treatment of cardiovascular diseases: state of the art and future directions

MM Ottaviani, F Vallone, S Micera… - Frontiers in …, 2022‏ - frontiersin.org
The autonomic nervous system exerts a fine beat-to-beat regulation of cardiovascular
functions and is consequently involved in the onset and progression of many cardiovascular …

The present and future of neural interfaces

D Valeriani, F Santoro, M Ienca - Frontiers in Neurorobotics, 2022‏ - frontiersin.org
The 2020's decade will likely witness an unprecedented development and deployment of
neurotechnologies for human rehabilitation, personalized use, and cognitive or other …

Towards enhanced functionality of vagus neuroprostheses through in silico optimized stimulation

F Ciotti, R John, N Katic Secerovic, N Gozzi… - Nature …, 2024‏ - nature.com
Bioelectronic therapies modulating the vagus nerve are promising for cardiovascular,
inflammatory, and mental disorders. Clinical applications are however limited by side-effects …

Highly efficient modeling and optimization of neural fiber responses to electrical stimulation

MA Hussain, WM Grill, NA Pelot - Nature Communications, 2024‏ - nature.com
Peripheral neuromodulation has emerged as a powerful modality for controlling
physiological functions and treating a variety of medical conditions including chronic pain …

ASCENT (Automated Simulations to Characterize Electrical Nerve Thresholds): A pipeline for sample-specific computational modeling of electrical stimulation of …

ED Musselman, JE Cariello, WM Grill… - PLoS computational …, 2021‏ - journals.plos.org
Electrical stimulation and block of peripheral nerves hold great promise for treatment of a
range of disease and disorders, but promising results from preclinical studies often fail to …

[كتاب][B] Electric brain signals: foundations and applications of biophysical modeling

G Halnes, TV Ness, S Næss, E Hagen, KH Pettersen… - 2024‏ - books.google.com
It is common to study the electric activity of neurons by measuring the electric potential in the
extracellular space of the brain. However, interpreting such measurements requires …

A finite element method framework to model extracellular neural stimulation

A Fellner, A Heshmat, P Werginz… - Journal of Neural …, 2022‏ - iopscience.iop.org
Objective. Increasing complexity in extracellular stimulation experiments and neural implant
design also requires realistic computer simulations capable of modeling the neural activity of …

Intrafascicular peripheral nerve stimulation produces fine functional hand movements in primates

M Badi, S Wurth, I Scarpato, E Roussinova… - Science Translational …, 2021‏ - science.org
Restoring dexterous hand control is critical for people with paralysis. Approaches based on
surface or intramuscular stimulation provide limited finger control, generate insufficient force …

Non-rectangular neurostimulation waveforms elicit varied sensation quality and perceptive fields on the hand

R Collu, EJ Earley, M Barbaro, M Ortiz-Catalan - Scientific Reports, 2023‏ - nature.com
Electrical stimulation of the nerves is known to elicit distinct sensations perceived in distal
parts of the body. The stimulation is typically modulated in current with charge-balanced …

Recalibration of neuromodulation parameters in neural implants with adaptive Bayesian optimization

G Aiello, G Valle, S Raspopovic - Journal of Neural Engineering, 2023‏ - iopscience.iop.org
Objective. Neuromodulation technology holds promise for treating conditions where
physiological mechanisms of neural activity have been affected. To make treatments efficient …