Branched chain amino acids (BCAAs) are essential for protein homeostasis, energy
balance, and signaling pathways. Changes in BCAA homeostasis have emerged as pivotal …

There is considerable heterogeneity in the cardiometabolic abnormalities associated with
obesity. We evaluated multi-organ system metabolic function in 20 adults with metabolically …

Brown adipose tissue (BAT) is best known for thermogenesis. Rodent studies demonstrated
that enhanced BAT thermogenesis is tightly associated with increased energy expenditure …

Elevated levels of circulating branched-chain amino acids (BCAAs) and their associated
metabolites have been strongly linked to insulin resistance and type 2 diabetes. Despite …

Background High-protein diets are often enriched with branched-chain amino acids
(BCAAs) known to enhance protein synthesis and provide numerous physiological benefits …

Background The branched-chain amino acids (BCAAs) to tyrosine (Tyr) ratio (BTR) test is
used to evaluate the progression of chronic liver disease (CLD). However, the differences …

Elevated levels of branched chain amino acids (BCAAs) and branched-chain α-ketoacids
are associated with cardiovascular and metabolic disease, but the molecular mechanisms …

Both heart failure and cardiometabolic disease are on the rise, and abnormal cardiac and
peripheral metabolism are central to the syndrome of heart failure. Advances in metabolomic …

Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Unique …

Interventions using dietary protein in obesity may be useful, especially during energy
restriction but also in sarcopenic obesity. Furthermore, metabolic profiles that encompass …