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Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy
W Gao, X Wang, Y Zhou, X Wang, Y Yu - Signal transduction and …, 2022 - nature.com
In recent years, immunotherapy represented by immune checkpoint inhibitors (ICIs) has led
to unprecedented breakthroughs in cancer treatment. However, the fact that many tumors …
to unprecedented breakthroughs in cancer treatment. However, the fact that many tumors …
Advances in the development of personalized neoantigen-based therapeutic cancer vaccines
E Blass, PA Ott - Nature reviews Clinical oncology, 2021 - nature.com
Within the past decade, the field of immunotherapy has revolutionized the treatment of many
cancers with the development and regulatory approval of various immune-checkpoint …
cancers with the development and regulatory approval of various immune-checkpoint …
Engineered exosomes as an in situ DC-primed vaccine to boost antitumor immunity in breast cancer
L Huang, Y Rong, X Tang, K Yi, P Qi, J Hou, W Liu… - Molecular cancer, 2022 - Springer
Abstract Background Dendritic cells (DCs) are central for the initiation and regulation of
innate and adaptive immunity in the tumor microenvironment. As such, many kinds of DC …
innate and adaptive immunity in the tumor microenvironment. As such, many kinds of DC …
Harnessing innate immune pathways for therapeutic advancement in cancer
The innate immune pathway is receiving increasing attention in cancer therapy. This
pathway is ubiquitous across various cell types, not only in innate immune cells but also in …
pathway is ubiquitous across various cell types, not only in innate immune cells but also in …
Augmenting immunotherapy via bioinspired MOF‐based ROS homeostasis disruptor with nanozyme‐cascade reaction
R Wang, M Qiu, L Zhang, M Sui, L **ao, Q Yu… - Advanced …, 2023 - Wiley Online Library
Despite its remarkable clinical breakthroughs, immune checkpoint blockade (ICB) therapy
remains limited by the insufficient immune response in the “cold” tumor. Nanozyme‐based …
remains limited by the insufficient immune response in the “cold” tumor. Nanozyme‐based …
Myeloid cell-targeted therapies for solid tumours
Myeloid cells are the most abundant immune components of the tumour microenvironment,
where they have a variety of functions, ranging from immunosuppressive to …
where they have a variety of functions, ranging from immunosuppressive to …
Biomimetic and bioinspired nano‐platforms for cancer vaccine development
The advent of immunotherapy has revolutionized the treating modalities of cancer. Cancer
vaccine, aiming to harness the host immune system to induce a tumor‐specific killing effect …
vaccine, aiming to harness the host immune system to induce a tumor‐specific killing effect …
Close the cancer–immunity cycle by integrating lipid nanoparticle–mRNA formulations and dendritic cell therapy
Effective cancer immunotherapy is usually blocked by immunosuppressive factors in the
tumour microenvironment, resulting in tumour promotion, metastasis and recurrence. Here …
tumour microenvironment, resulting in tumour promotion, metastasis and recurrence. Here …
Multifaceted role of redox pattern in the tumor immune microenvironment regarding autophagy and apoptosis
Y Ren, R Wang, S Weng, H Xu, Y Zhang, S Chen… - Molecular cancer, 2023 - Springer
The reversible oxidation-reduction homeostasis mechanism functions as a specific signal
transduction system, eliciting related physiological responses. Disruptions to redox …
transduction system, eliciting related physiological responses. Disruptions to redox …
Trial watch: Dendritic cell (DC)-based immunotherapy for cancer
Dendritic cell (DC)-based vaccination for cancer treatment has seen considerable
development over recent decades. However, this field is currently in a state of flux toward …
development over recent decades. However, this field is currently in a state of flux toward …