Cellular exposure to ionizing radiation leads to oxidizing events that alter atomic structure
through direct interactions of radiation with target macromolecules or via products of water …

Emerging evidence now indicates that mitochondria are central regulators of neural stem
cell (NSC) fate decisions and are crucial for both neurodevelopment and adult …

Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …

As the primary cellular location for respiration and energy production, mitochondria serve in
a critical capacity to the cell. Yet, by virtue of this very function of respiration, mitochondria …

Glucocorticoids released from the adrenal gland in response to stress-induced activation of
the hypothalamic-pituitary-adrenal (HPA) axis induce activity in the cellular reduction …

Neural stem/progenitor cell (NSPC) proliferation and self‐renewal, as well as insult‐induced
differentiation, decrease markedly with age. The molecular mechanisms responsible for …

Many people around the world suffer from some form of paralysis caused by spinal cord
injury (SCI), which has an impact on quality and life expectancy. The spinal cord is part of …

Mitochondrial dysfunction is a common feature of many genetic disorders that target the
brain and cognition. However, the exact role these organelles play in the etiology of such …

The importance of mitochondria in energy metabolism, signal transduction and aging in post-
mitotic tissues has been well established. Recently, the crucial role of mitochondrial-linked …