Study the solvation effect on 6-phenyl-2-thioxo-1, 2-dihydropyridine-3-carbonitrile derivatives by TD-DFT calculations and molecular dynamics simulations

MK Abdel-Latif, HR Abd El-Mageed… - Journal of Molecular …, 2020 - Elsevier
The electronic structure of 6-phenyl-2-thioxo-1, 2-dihydropyridine-3-carbonitrile (2-mercapto-
6-phenylpyridine-3-carbonitrile) and its some derivatives have been studied both …

HIV-1 and HSV-1 virus activities of some new polycyclic nucleoside pyrene candidates

NM Khalifa, MA Al-Omar, AEGE Amr… - International Journal of …, 2013 - Elsevier
In continuation of our previous work, a novel series of polycyclic derivatives 2–8
incorporated heterocyclic and sugar moieties were synthesized by using pyren-1-aldehyde …

Synthesis, characterization and reactivity of carbohydrate platinum (IV) complexes with thioglycoside ligands

C Vetter, P Pornsuriyasak, J Schmidt, NP Rath… - Dalton …, 2010 - pubs.rsc.org
Reactions of fac-[PtMe3 (4, 4′-R2bpy)(Me2CO)][BF4](R= H, 1a; tBu, 1b) and fac-[PtMe3
(OAc-κ2O, O′)(Me2CO)](2), respectively, with thioglycosides containing thioethyl (ch-SEt) …

Synthesis, characterization and pharmacological investigations of some novel heterocyclic derivatives incorporating pyrene and sugar moieties

NM Khalifa, MS Mohamed, ME Zaki… - Research on Chemical …, 2014 - Springer
A series of substituted pyrene derivatives 2–15 incorporated heterocyclic and sugar moieties
were synthesized and evaluated as antiviral activities using 1-acetylpyrene as a starting …

[PDF][PDF] Novel fused thienopyridine and pyrazolopyridine derivatives: Synthesis, characterization and cytotoxicity

MAA Elneairy, SM Eldine, ASI Mohamed - Der. Pharma Chem, 2015 - researchgate.net
Several new of fused thienopyridine and pyrazolopyridine derivatives were synthesized via
the reactions of both compounds 2-Carbohydrazide 2 and 3-aminopyrazolopyridine 14 with …

Benzophenone Derivatives Showed Dual Anti-Inflammatory and Antiproliferative Activities by Inhibiting COX Enzymes and Promote Cyclin E Downregulation

LRS Folquitto, TB Souza, JP Januario… - Journal of the Brazilian …, 2022 - SciELO Brasil
Considering the promising antitumor effects of compounds with dual anti-inflammatory and
antiproliferative activities, thus benzophenones analogs (2-7) were evaluated on in vivo anti …

Synthesis and characterization of novel chalcones linked 3-[1-(3-chlorophenyl)-3-(pyren-1-yl)]-1H-pyrazole moiety

NM Khalifa, MA Al-Omar, OM Ali - Russian Journal of General Chemistry, 2017 - Springer
New series of pyrenyl–pyrazole based chalcones have been synthesized and characterized
via the condensation of 1-(3-chlorophenyl)-3-(pyren-1-yl)-1 H-pyrazole-4-carbaldehyde with …

Synthesis and reactions of some new (E)-2-сyano-N′-[1-(pyren-3-yl)ethylidene]acetohydrazide derivatives

NM Khalifa, MA Al-Omar, OM Ali - Russian Journal of General Chemistry, 2017 - Springer
Abstract Some novel (E)-2-cyano-3-(substituted phenyl/dimethylamino)-N′-[1-(pyren-3-yl)]
acrylohydrazides and benzochromenone-2-carbohydrazide derivatives were synthesized by …

New Polysubstituted Pyrazole Derivatives: Synthesis and Cytotoxicity Studies

NM Khalifa, HH Fahmy, ES Nossier… - Russian Journal of …, 2020 - Springer
Abstract Several new 1, 3, 4-trisubstituted pyrazoles are synthesized from (E)-3-[1-(3-
chlorophenyl)-3-(4-methoxyphenyl)-1 H-pyrazol-4-yl]-1-(pyridin-3-yl) prop-2-en-1-one and …

Recent development in sugar derivatives

M Rajasekar - Bioactive carbohydrates and dietary fibre, 2016 - Elsevier
In recent years, the considerable progress has been made in the synthesis of glycosides.
The challenging chemistry, due to its versatility, glycosides play a key role in develo** …