Liver fibrosis should be assessed in all individuals with chronic liver disease as it predicts
the risk of future liver-related morbidity and thus need for treatment, monitoring and …

Background & Aims Magnetic resonance elastography (MRE) and transient elastography
(TE) are noninvasive techniques for detection of liver fibrosis. Single-center studies have …

Abbreviations: AASLD, American Association for the Study of Liver Diseases; AI, artificial
intelligence; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUROC …

Dysregulation of the gut microbiome has been implicated in the progression of non-alcoholic
fatty liver disease (NAFLD) to advanced fibrosis and cirrhosis. To determine the diagnostic …

Chronic liver diseases often result in the development of liver fibrosis and ultimately,
cirrhosis. Treatment strategies and prognosis differ greatly depending on the severity of liver …

The presence of cirrhosis in nonalcoholic-fatty-liver-disease (NAFLD) is the most important
predictor of liver-related mortality. Limited data exist concerning the diagnostic accuracy of …

Abstract Background and Aims Surrogate endpoints that predict complications are
necessary for assessment and approval of NASH therapies. We assessed associations …

Background & Aims We conducted an individual patient data meta-analysis to establish
stiffness cut-off values for magnetic resonance elastography (MRE) in staging liver fibrosis …

Liver fibrosis is characterized by the accumulation of extracellular matrix proteins such as
collagen in the liver interstitial space. All causes of chronic liver disease may lead to fibrosis …

Nonalcoholic fatty liver disease (NAFLD) is generally considered a silent and potentially
reversible condition. The subtype of NAFLD that can be classified as nonalcoholic …