Clinical predictors of therapeutic response to antipsychotics in schizophrenia
M Carbon, CU Correll - Dialogues in clinical neuroscience, 2014 - Taylor & Francis
The search for clinical outcome predictors for schizophrenia is as old as the field of
psychiatry. However, despite a wealth of large, longitudinal studies into prognostic factors …
psychiatry. However, despite a wealth of large, longitudinal studies into prognostic factors …
Early improvement as a predictor of later response to antipsychotics in schizophrenia: a diagnostic test review
Objective: How long clinicians should wait before considering an antipsychotic ineffective
and changing treatment in schizophrenia is an unresolved clinical question. Guidelines …
and changing treatment in schizophrenia is an unresolved clinical question. Guidelines …
Pharmacological treatment of negative symptoms in schizophrenia: update and proposal of a clinical algorithm
The clinical presentation of schizophrenia encompasses symptoms divided into three
dimensions: positive, negative, and cognitive. Negative symptoms (NS), in particular, have a …
dimensions: positive, negative, and cognitive. Negative symptoms (NS), in particular, have a …
Factors associated with relapse in schizophrenia despite adherence to long-acting injectable antipsychotic therapy
L Alphs, HA Nasrallah, CA Bossie, DJ Fu… - International clinical …, 2016 - journals.lww.com
Many patients with schizophrenia will relapse despite uninterrupted antipsychotic (AP) long-
acting therapy (LAT). This exploratory analysis examined variables associated with relapse …
acting therapy (LAT). This exploratory analysis examined variables associated with relapse …
Duration of untreated psychosis predicts functional and clinical outcome in children and adolescents with first-episode psychosis: a 2-year longitudinal study
Longer duration of untreated psychosis (DUP) in adult patients with first-episode psychosis
(FEP) has been associated with poor clinical and social outcomes. We aimed to estimate the …
(FEP) has been associated with poor clinical and social outcomes. We aimed to estimate the …
Social withdrawal as a trans-diagnostic predictor of short-term remission: a meta-analysis of five clinical cohorts
Social withdrawal is an early manifestation of several neuropsychiatric disorders, and it is
characterised by a gradual disengagement from social interactions, potentially leading to …
characterised by a gradual disengagement from social interactions, potentially leading to …
[HTML][HTML] Treatment response in first-episode schizophrenia
R Schennach, M Riedel, R Musil… - Clinical …, 2012 - ncbi.nlm.nih.gov
First episode schizophrenia (FES) patients tend to be more responsive to treatment. An
adequate response has been associated with a favourable long-term course in FES …
adequate response has been associated with a favourable long-term course in FES …
Negative symptoms in first‐episode psychosis: Clinical correlates and 1‐year follow‐up outcomes in London Early Intervention Services
Aim Negative symptoms (NS) have been associated with poor outcome and remain difficult
to treat in patients with psychosis. This study examined the association of NS with clinical …
to treat in patients with psychosis. This study examined the association of NS with clinical …
Electroconvulsive therapy improves antipsychotic and somnographic responses in adolescents with first-episode psychosis—A case–control study
ZJ Zhang, YC Chen, HN Wang, HH Wang, YY Xue… - Schizophrenia …, 2012 - Elsevier
OBJECTIVE: Previous studies have demonstrated the effectiveness of electroconvulsive
therapy (ECT) in pharmacotherapy-resistant neuropsychiatric conditions. This study aimed …
therapy (ECT) in pharmacotherapy-resistant neuropsychiatric conditions. This study aimed …
A longitudinal study on the relationship between duration of untreated psychosis and executive function in early-onset first-episode psychosis
Background The relationship between duration of untreated psychosis (DUP) and executive
function (EF) in patients with first-episode psychosis (FEP) is controversial. We aim to assess …
function (EF) in patients with first-episode psychosis (FEP) is controversial. We aim to assess …