Interpretation of the role of germline and somatic non-coding mutations in cancer: expression and chromatin conformation informed analysis
Background There has been extensive scrutiny of cancer driving mutations within the exome
(especially amino acid altering mutations) as these are more likely to have a clear impact on …
(especially amino acid altering mutations) as these are more likely to have a clear impact on …
Genome-wide map** of regulatory variants for temperature-and salinity-adaptive genes reveals genetic basis of genotype-by-environment interaction in …
K Zhang, Q Yang, M Du, Z Zhang, W Wang… - Environmental …, 2023 - Elsevier
Regulatory variants in gene expression serve as bridges linking genetic variation and
phenotypic plasticity. Environmental conditions typically influence the effects of regulatory …
phenotypic plasticity. Environmental conditions typically influence the effects of regulatory …
LncRNA SNHG11 aggravates cell proliferation and migration in triple‑negative breast cancer via sponging miR‑2355‑5p and targeting CBX5
L Yu, W Zhang, P Wang, Q Zhang… - Experimental and …, 2021 - spandidos-publications.com
Triple‑negative breast cancer (TNBC) is one of the most common malignances worldwide.
Concurrently, the incidence of TNBC has continued to rise in recent years. It is reported that …
Concurrently, the incidence of TNBC has continued to rise in recent years. It is reported that …
LncRNA SNHG11 accelerates the progression of lung adenocarcinoma via activating Notch pathways
Y Deng, L Zhang - Pathology-Research and Practice, 2022 - Elsevier
Background Numerous researches have emphasized that long non-coding RNAs (lncRNAs)
have a close association with the biological process in multiple cancers including lung …
have a close association with the biological process in multiple cancers including lung …
An ovarian cancer susceptible gene prediction method based on deep learning methods
L Ye, Y Zhang, X Yang, F Shen, B Xu - Frontiers in Cell and …, 2021 - frontiersin.org
Ovarian cancer (OC) is one of the most fatal diseases among women all around the world. It
is highly lethal because it is usually diagnosed at an advanced stage which may reduce the …
is highly lethal because it is usually diagnosed at an advanced stage which may reduce the …
MiR‐3130‐5p is an intermediate modulator of 2q33 and influences the invasiveness of lung adenocarcinoma by targeting NDUFS1
J Zhan, S Sun, Y Chen, C Xu, Q Chen, M Li… - Cancer …, 2021 - Wiley Online Library
Genome‐wide association studies (GWAS) have reported a handful of loci associated with
lung cancer risk, of which the pathogenic pathways are largely unknown. We performed cis …
lung cancer risk, of which the pathogenic pathways are largely unknown. We performed cis …
A Comprehensive Investigation of Genomic Variants in Prostate Cancer Reveals 30 Putative Regulatory Variants
Prostate cancer (PC) is the most frequently diagnosed non-skin cancer in the world.
Previous studies have shown that genomic alterations represent the most common …
Previous studies have shown that genomic alterations represent the most common …
The impact of inherited genetic variation on DNA methylation in prostate cancer and benign tissues of African American and European American men
D Delgado, M Gillard, L Tong, K Demanelis… - … Biomarkers & Prevention, 2024 - AACR
Abstract Background: American men of African ancestry (AA) have higher prostate cancer
incidence and mortality rates compared with American men of European ancestry (EA) …
incidence and mortality rates compared with American men of European ancestry (EA) …
Genome‐wide association study identifies novel single nucleotide polymorphisms having age‐specific effect on prostate‐specific antigen levels
Background Testing for prostate‐specific antigen (PSA) levels in blood are widely used and
associated with prostate cancer risk and outcome. After puberty, PSA levels increase by age …
associated with prostate cancer risk and outcome. After puberty, PSA levels increase by age …
An Integrative analysis of chromatin interactions, gene expression and genomic variants identifies 30 likely regulatory variants in Prostate Cancer
Prostate cancer (PC) is the most frequently diagnosed non-skin cancer in the world.
Previous studies showed that genomic alterations represent the most common mechanism …
Previous studies showed that genomic alterations represent the most common mechanism …