Looking beyond COVID-19 vaccine phase 3 trials
After the recent announcement of COVID-19 vaccine efficacy in clinical trials by several
manufacturers for protection against severe disease, a comprehensive post-efficacy strategy …
manufacturers for protection against severe disease, a comprehensive post-efficacy strategy …
Antibodies to combat viral infections: development strategies and progress
Monoclonal antibodies (mAbs) are appealing as potential therapeutics and prophylactics for
viral infections owing to characteristics such as their high specificity and their ability to …
viral infections owing to characteristics such as their high specificity and their ability to …
[HTML][HTML] What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2
The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
has caused more than 1 million deaths in the first 6 months of the pandemic and huge …
has caused more than 1 million deaths in the first 6 months of the pandemic and huge …
The use of viral vectors in vaccine development
Vaccines represent the single most cost-efficient and equitable way to combat and eradicate
infectious diseases. While traditional licensed vaccines consist of either …
infectious diseases. While traditional licensed vaccines consist of either …
Next-generation vaccine platforms for COVID-19
D van Riel, E de Wit - Nature materials, 2020 - nature.com
Consensus among experts is that only an effective COVID-19 vaccine will end the
pandemic. This Comment focuses on how this pandemic has accelerated the development …
pandemic. This Comment focuses on how this pandemic has accelerated the development …
Vaccines for COVID-19
JS Tregoning, ES Brown… - Clinical & …, 2020 - academic.oup.com
Since the emergence of COVID-19, caused by the SARS-CoV-2 virus at the end of 2019,
there has been an explosion of vaccine development. By 24 September 2020, a staggering …
there has been an explosion of vaccine development. By 24 September 2020, a staggering …
Ebola virus disease
Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus
(EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission …
(EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission …
The long road toward COVID-19 herd immunity: vaccine platform technologies and mass immunization strategies
LSF Frederiksen, Y Zhang, C Foged… - Frontiers in …, 2020 - frontiersin.org
There is an urgent need for effective countermeasures against the current emergence and
accelerating expansion of coronavirus disease 2019 (COVID-19), caused by severe acute …
accelerating expansion of coronavirus disease 2019 (COVID-19), caused by severe acute …
Develo** therapeutic approaches for twenty-first-century emerging infectious viral diseases
RM Meganck, RS Baric - Nature medicine, 2021 - nature.com
The twenty-first century has already recorded more than ten major epidemic or pandemic
virus emergence events, including the ongoing and devastating coronavirus disease 2019 …
virus emergence events, including the ongoing and devastating coronavirus disease 2019 …
Public health emergencies of international concern: a historic overview
A Wilder-Smith, S Osman - Journal of travel medicine, 2020 - academic.oup.com
Abstract Rationale The International Health Regulations (IHR) have been the governing
framework for global health security since 2007. Declaring public health emergencies of …
framework for global health security since 2007. Declaring public health emergencies of …