The immense diversity of extracellular matrix (ECM) proteins confers distinct biochemical
and biophysical properties that influence cell phenotype. The ECM is highly dynamic as it is …

The existence of orderly structures, such as tissues and organs is made possible by cell
adhesion, ie, the process by which cells attach to neighbouring cells and a supporting …

Key cellular decisions, such as proliferation or growth arrest, typically occur at spatially
defined locations within tissues. Loss of this spatial control is a hallmark of many diseases …

Cell-substrate interactions play a crucial role in the design of better biomaterials and
integration of implants with the tissues. Adhesion is the binding process of the cells to the …

Signalling from the extracellular matrix (ECM) is a fundamental cellular input that sustains
proliferation, opposes cell death and regulates differentiation. Through integrins, cells …

The extracellular matrix (ECM) serves diverse functions and is a major component of the
cellular microenvironment. The ECM is a highly dynamic structure, constantly undergoing a …

The clinical demand for scaffolds and the diversity of available polymers provide freedom in
the fabrication of scaffolds to achieve successful progress in bone tissue engineering (BTE) …

Successful tissue regeneration requires a scaffold with tailorable biodegradability, tissue-
like mechanical properties, structural similarity to extracellular matrix (ECM), relevant …

Degradable and cell-compatible hydrogels can be designed to mimic the physical and
biochemical characteristics of native extracellular matrices and provide tunability of …

Simple Summary The cytoskeleton is a network of protein fibres within cells that provide
structure and support intracellular transport. Focal adhesions are protein complexes …