Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …

Selective transport of solutes across a membrane is critical for many biological, water
treatment and energy conversion and storage systems. When a charged membrane is …

Although textbook pictures depict the cell nucleus as a simple ovoid object, it is now clear
that it adopts a large variety of shapes in tissues. When cells deform, because of cell …

Cellular growth is the result of passive physical constraints and active biological processes.
Their interplay leads to the appearance of robust and ubiquitous scaling laws relating …

The volume of the cell nucleus varies across cell types and species and is commonly
thought to be determined by the size of the genome and degree of chromatin compaction …

Many measurements of chromatin packing in the nucleus of fixed cells indicate that a large
fraction of the nuclear volume is filled with chromatin. Our measurements of the spatial …

Cell mass and chemical composition are important aggregate cellular properties that are
especially relevant to physiological processes, such as growth control and tissue …

In eukaryotes, cytoplasmic and nuclear volumes are tightly regulated to ensure proper cell
homeostasis. However, current methods to measure cytoplasmic and nuclear volumes …

Sustained proliferation is a significant driver of cancer progression. Cell-cycle advancement
is coupled with cell size, but it remains unclear how multiple cells interact to control their …

Mechanics has been a central focus of physical biology in the past decade. In comparison,
how cells manage their size is less understood. Here, we show that a parameter central to …