Protein switches are ubiquitous in biological signal transduction systems, enabling cells to
sense and respond to a variety of molecular queues in a rapid, specific, and integrated …

DNA computing represents a subfield of molecular computing with the potential to become a
significant area of next-generation computation due to the high programmability inherent in …

Inspired by the remarkable ability of natural protein switches to sense and respond to a wide
range of environmental queues, here we report a strategy to engineer synthetic protein …

Enzymes play a pivotal role in regulating numerous bodily functions. Thus, there is a
growing need for develo** sensors enabling real‐time monitoring of enzymatic activity …

Living cells regulate key cellular processes by spatial organization of catalytically active
proteins in higher-order signalling complexes. These act as organizing centres to facilitate …

Reversible regulation of enzyme activity by chemical and physical stimuli is often achieved
by incorporating stimuli-responsive domains in the enzyme of interest. However, this method …

Host–guest complexes are emerging as powerful components in functional systems with
applications ranging from materials to biomedicine. In particular, CB7 based host–guest …

DNA-based molecular circuits allow autonomous signal processing, but their actuation has
relied mostly on RNA/DNA-based inputs, limiting their application in synthetic biology …

Dynamic interactions of enzymes, including programmable configuration and cycling of
enzymes, play important roles in the regulation of cellular metabolism. Here, we constructed …

Nature uses dynamic molecular platforms for the recruitment of weakly associating proteins
into higher-order assemblies to achieve spatiotemporal control of signal transduction …