Revisiting inflammatory bowel disease: pathology, treatments, challenges and emerging therapeutics including drug leads from natural products
Inflammatory bowel disease (IBD) is a chronic and life-long disease characterized by
gastrointestinal tract inflammation. It is caused by the interplay of the host's genetic …
gastrointestinal tract inflammation. It is caused by the interplay of the host's genetic …
Raging the war against inflammation with natural products
Over the last few decade Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are the drugs of
choice for treating numerous inflammatory diseases including rheumatoid arthritis. The …
choice for treating numerous inflammatory diseases including rheumatoid arthritis. The …
In vitro anti-inflammatory activity of spherical silver nanoparticles and monodisperse hexagonal gold nanoparticles by fruit extract of Prunus serrulata: a green …
Recently, green metal nanoparticles have received global attention owing to their
economical synthesis, biocompatible nature, widespread biomedical and environmental …
economical synthesis, biocompatible nature, widespread biomedical and environmental …
An oriental medicine, Hyungbangpaedok-San attenuates motor paralysis in an experimental model of multiple sclerosis by regulating the T cell response
The preventive and therapeutic mechanisms in multiple sclerosis are not clearly understood.
We investigated whether Hyungbangpaedok-san (HBPDS), a traditional herbal medicine …
We investigated whether Hyungbangpaedok-san (HBPDS), a traditional herbal medicine …
Anti-inflammatory properties of anthraquinones and their relationship with the regulation of P-glycoprotein function and expression
There is a growing interest in natural products that potentially have anti-inflammatory
properties and inhibit P-glycoprotein (P-gp) function. In this report, we assessed the effects …
properties and inhibit P-glycoprotein (P-gp) function. In this report, we assessed the effects …
Kaurenoic Acid from Sphagneticola trilobata Inhibits Inflammatory Pain: Effect on Cytokine Production and Activation of the NO–Cyclic GMP–Protein Kinase G–ATP …
Kaurenoic acid [ent-kaur-16-en-19-oic acid (1)] is a diterpene present in several plants
including Sphagneticola trilobata. The only documented evidence for its antinociceptive …
including Sphagneticola trilobata. The only documented evidence for its antinociceptive …
[HTML][HTML] Anti-Inflammatory and Anticancer Effects of Kaurenoic Acid in Overcoming Radioresistance in Breast Cancer Radiotherapy
TW Kim, SG Ko - Nutrients, 2024 - mdpi.com
Background/Objectives: Peroxisome proliferator–activated receptor γ (PPARγ) plays a key
role in mediating anti-inflammatory and anticancer effects in the tumor microenvironment …
role in mediating anti-inflammatory and anticancer effects in the tumor microenvironment …
Kaurenoic acid nanocarriers regulates cytokine production and inhibit breast cancer cell migration
KCB Ferreira, ABC dos Santos Valle… - Journal of Controlled …, 2022 - Elsevier
Breast cancer is the type of cancer with the highest incidence in women around the world.
Noteworthy, the triple-negative subtype affects 20% of the patients while presenting the …
Noteworthy, the triple-negative subtype affects 20% of the patients while presenting the …
Traditional uses, phytochemistry, pharmacology, toxicity and quality control of medicinal genus Aralia: A review
Y Xu, J Liu, Y Zeng, S **, W Liu, Z Li, X Qin… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Aralia, which belongs to Araliaceae family, is mainly
distributed in Asia, such as China, Japan and South Korea. It has a long medicinal history …
distributed in Asia, such as China, Japan and South Korea. It has a long medicinal history …
Insight into the molecular mechanism of a herbal injection by integrating network pharmacology and in vitro
Y Ma, X Zhang, Z Su, N Li, L Cao, G Ding… - Journal of …, 2015 - Elsevier
Chinese medical herbs could treat complex diseases through the synergistic effect of multi-
components, multi-targets and multi-channels. However, it was difficult to systematically …
components, multi-targets and multi-channels. However, it was difficult to systematically …