Stimuli‐responsive crosslinked nanomedicine for cancer treatment

X Xue, H Qu, Y Li - Exploration, 2022 - Wiley Online Library
Nanomedicines are attractive paradigms to deliver drugs, contrast agents,
immunomodulators, and gene editors for cancer therapy and diagnosis. However, the …

Current challenges and opportunities of photodynamic therapy against cancer

RV Huis in 't Veld, J Heuts, S Ma, LJ Cruz… - Pharmaceutics, 2023 - mdpi.com
BACKGROUND: Photodynamic therapy (PDT) is an established, minimally invasive
treatment for specific types of cancer. During PDT, reactive oxygen species (ROS) are …

Microneedle-assisted topical delivery of photodynamically active mesoporous formulation for combination therapy of deep-seated melanoma

HP Tham, K Xu, WQ Lim, H Chen, M Zheng… - ACS …, 2018 - ACS Publications
Topical treatment using photodynamic therapy (PDT) for many types of skin cancers has
largely been limited by the inability of existing photosensitizers to penetrate into the deep …

Silicon-containing nanomedicine and biomaterials: materials chemistry, multi-dimensional design, and biomedical application

L Chen, S Zhang, Y Duan, X Song, M Chang… - Chemical Society …, 2024 - pubs.rsc.org
The invention of silica-based bioactive glass in the late 1960s has sparked significant
interest in exploring a wide range of silicon-containing biomaterials from the macroscale to …

Development of a light-controlled nanoplatform for direct nuclear delivery of molecular and nanoscale materials

YX Zhu, HR Jia, GY Pan, NW Ulrich… - Journal of the …, 2018 - ACS Publications
Research on nanomedicines has rapidly progressed in the past few years. However, due to
the limited size of nuclear pores (9–12 nm), the nuclear membrane remains a difficult barrier …

Understanding the significant role of SiOSi bonds: organosilicon materials as powerful platforms for bioimaging

Y Zuo, X Liang, J Yin, Z Gou, W Lin - Coordination Chemistry Reviews, 2021 - Elsevier
Fluorescence imaging is one of the most powerful methods for the spatial and temporal
visualization of bio-species in living systems. Various fluorescent materials have obtained …

Oxygen‐evolving mesoporous organosilica coated prussian blue nanoplatform for highly efficient photodynamic therapy of tumors

ZL Yang, W Tian, Q Wang, Y Zhao, YL Zhang… - Advanced …, 2018 - Wiley Online Library
Oxygen (O2) plays a critical role during photodynamic therapy (PDT), however, hypoxia is
quite common in most solid tumors, which limits the PDT efficacy and promotes the tumor …

Highly biocompatible chlorin e6-loaded chitosan nanoparticles for improved photodynamic cancer therapy

YF Ding, S Li, L Liang, Q Huang, L Yuwen… - … Applied Materials & …, 2018 - ACS Publications
The photosensitizer Chlorin e6 (Ce6) has been frequently employed for photodynamic
therapy (PDT) of cancer; however, its nonspecific toxicity has limited its clinical applications …

Emerging Single‐Atom Catalysts/Nanozymes for Catalytic Biomedical Applications

Z Wang, FG Wu - Advanced Healthcare Materials, 2022 - Wiley Online Library
Single‐atom catalysts (SACs) are a type of atomically dispersed nanozymes with the highest
atom utilization, which employ low‐coordinated single atoms as the catalytically active sites …

Use of polyhedral oligomeric silsesquioxane (POSS) in drug delivery, photodynamic therapy and bioimaging

P Loman-Cortes, T Binte Huq, JL Vivero-Escoto - Molecules, 2021 - mdpi.com
Polyhedral oligomeric silsesquioxanes (POSS) have attracted considerable attention in the
design of novel organic-inorganic hybrid materials with high performance capabilities …