Immunotherapies have revolutionized the treatment paradigms of various types of cancers.
However, most of these immunomodulatory strategies focus on harnessing adaptive …

Natural killer (NK) cells, a subgroup of innate lymphoid cells, act as the first line of defense
against cancer. Although some evidence shows that NK cells can develop in secondary …

Chemokines are chemo tactic cyto kines that control the migratory patterns and positioning
of all immune cells. Although chemokines were initially appreciated as important mediators …

Natural killer (NK) cells have long been considered to be a homogenous population of
innate lymphocytes with limited phenotypic and functional diversity. However, recent …

Sphingosine 1-phosphate (S1P) is a membrane-derived lysophospholipid that acts primarily
as an extracellular signaling molecule. Signals initiated by S1P are transduced by five G …

Chemokines govern leukocyte migration by attracting cells that express their cognate
ligands. Many cancer types show altered chemokine secretion profiles, favoring the …

Tissue-resident memory T (TRM) cells provide long-lasting immune protection. One of the
key events controlling TRM cell development is the local retention of TRM cell precursors …

The identification of distinct tissue-specific natural killer (NK) cell populations that apparently
mature from local precursor populations has brought new insight into the diversity and …

Trail+DX5 Eomes natural killer (NK) cells arise in the mouse fetal liver and persist in the
adult liver. Their relationships with Trail DX5+ NK cells remain controversial. We generated …

Lysophospholipids encompass a diverse range of small, membrane‐derived phospholipids
that act as extracellular signals. The signalling properties are mediated by 7 …