Chronic hyperglycemia and the corresponding glucotoxicity are the main pathogenic
mechanisms of diabetes and its complications. Streptozotocin (STZ)-induced diabetic animal …

Nitrosamines mediate their mutagenic effects by causing DNA damage, oxidative stress,
lipid peroxidation, and pro-inflammatory cytokine activation, which lead to increased cellular …

Medicinal plants attract growing interest in the therapeutic management of Diabetes mellitus.
Moringa oleifera is a remarkably nutritious vegetable with several antioxidant properties …

Glucose metabolism and insulin signaling disruptions in the brain have been proposed as a
likely etiology of Alzheimer's disease. The aim of the present study was to investigate the …

Background: Diabetic complications are the major contributor in the mortality of diabetic
patients despite controlling blood glucose level. In the journey of new drug discovery, animal …

Diabetes has reached epidemic levels in the whole world, and the use of bioactive
compounds that may have the capacity to prevent and treat diabetes is of great interest …

Background Hyperglycemia is common in extremely low gestational age newborns (ELGAN)
and is associated with increased mortality and morbidity, including abnormal …

Recent evidence suggests that transient hyperglycemia in extremely low birth weight infants
is strongly associated with the occurrence of retinopathy of prematurity (ROP). We propose a …

Several studies support the health-promoting benefits of lupins, particularly lupin proteins. It
has been demonstrated that Lupinus albus gamma conglutin (Cγ) protein lowered blood …

Diabetes mellitus is a product of low insulin sensibility and pancreatic β-cell insufficiency.
Rats with streptozotocin-induced diabetes during the neonatal period by the fifth day of age …