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[HTML][HTML] HuRdling senescence: HuR breaks BRAF-induced senescence in melanocytes and supports melanoma growth
JK Liebig, S Kuphal, AK Bosserhoff - Cancers, 2020 - mdpi.com
In addition to genetic changes, post-transcriptional events strongly contribute to the
progression of malignant tumors. The RNA-binding protein HuR (ELAVL1) is able to bind …
progression of malignant tumors. The RNA-binding protein HuR (ELAVL1) is able to bind …
Molecular targeting of HuR oncoprotein suppresses MITF and induces apoptosis in melanoma cells
R Ahmed, R Muralidharan, A Srivastava, SE Johnston… - Cancers, 2021 - mdpi.com
Simple Summary The human antigen R (HuR) protein regulates the expression of hundreds
of proteins in a cell that support tumor growth, drug resistance, and metastases. HuR is …
of proteins in a cell that support tumor growth, drug resistance, and metastases. HuR is …
[HTML][HTML] The human antigen R as an actionable super-hub within the network of cancer cell persistency and plasticity
R Merat - Translational Oncology, 2023 - Elsevier
In this perspective article, a clinically inspired phenotype-driven experimental approach is
put forward to address the challenge of the adaptive response of solid cancers to small …
put forward to address the challenge of the adaptive response of solid cancers to small …