Systematic review and meta-analysis of the effects of menopause hormone therapy on risk of Alzheimer's disease and dementia
M Nerattini, S Jett, C Andy, C Carlton… - Frontiers in aging …, 2023 - frontiersin.org
Introduction Despite a large preclinical literature demonstrating neuroprotective effects of
estrogen, use of menopausal hormone therapy (HT) for Alzheimer's disease (AD) risk …
estrogen, use of menopausal hormone therapy (HT) for Alzheimer's disease (AD) risk …
[HTML][HTML] The'middle-aging'brain
Middle age has historically been an understudied period of life compared to older age, when
cognitive and brain health decline are most pronounced, but the scope for intervention may …
cognitive and brain health decline are most pronounced, but the scope for intervention may …
Sex and gender differences in cognitive resilience to aging and Alzheimer's disease
Sex and gender—biological and social constructs—significantly impact the prevalence of
protective and risk factors, influencing the burden of Alzheimer's disease (AD; amyloid beta …
protective and risk factors, influencing the burden of Alzheimer's disease (AD; amyloid beta …
Spatial patterns of white matter hyperintensities: a systematic review
Background White matter hyperintensities are an important marker of cerebral small vessel
disease. This disease burden is commonly described as hyperintense areas in the cerebral …
disease. This disease burden is commonly described as hyperintense areas in the cerebral …
Menopause causes metabolic and cognitive impairments in a chronic cerebral hypoperfusion model of vascular contributions to cognitive impairment and dementia
OJ Gannon, JS Naik, D Riccio, FM Mansour… - Biology of sex …, 2023 - Springer
Background The vast majority of women with dementia are post-menopausal. Despite
clinical relevance, menopause is underrepresented in rodent models of dementia. Before …
clinical relevance, menopause is underrepresented in rodent models of dementia. Before …
[HTML][HTML] Intersectionality in Alzheimer's disease: the role of female sex and Black American race in the development and prevalence of Alzheimer's disease
It is well known that vascular factors and specific social determinants of health contribute to
dementia risk and that the prevalence of these risk factors differs according to race and sex …
dementia risk and that the prevalence of these risk factors differs according to race and sex …
[HTML][HTML] White matter hyperintensity distribution differences in aging and neurodegenerative disease cohorts
Abstract Introduction White matter hyperintensities (WMHs) are common magnetic
resonance imaging (MRI) findings in the aging population in general, as well as in patients …
resonance imaging (MRI) findings in the aging population in general, as well as in patients …
[HTML][HTML] Cerebral white matter hyperintensity volumes: normative age-and sex-specific values from 15 population-based cohorts comprising 14,876 individuals
White matter hyperintensities (WMH) increase with age, with marked interindividual
variation. There is a need for normative data by age and sex, to improve individualized WMH …
variation. There is a need for normative data by age and sex, to improve individualized WMH …
Association of cumulative lifetime exposure to female hormones with cerebral small vessel disease in postmenopausal women in the UK biobank
Background and Objectives Rates of cerebrovascular disease increase after menopause,
which is often attributed to the absence of hormones. It remains unknown whether the …
which is often attributed to the absence of hormones. It remains unknown whether the …
Bio-psycho-social factors' associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participants
Brain age refers to age predicted by brain features. Brain age has previously been
associated with various health and disease outcomes and suggested as a potential …
associated with various health and disease outcomes and suggested as a potential …