S-adenosylmethionine (AdoMet, also known as SAM and SAMe) is the principal biological
methyl donor synthesized in all mammalian cells but most abundantly in the liver …

Methionine adenosyltransferase (MAT) is an ubiquitous enzyme that catalyzes the synthesis
of S-adenosylmethionine from methionine and ATP. In mammals, there are two genes …

One-carbon metabolism is an essential branch of cellular metabolism that intersects with
epigenetic regulation. In this work, we show how formaldehyde (FA), a one-carbon unit …

S-adenosyl-l-methionine (SAMe; AdoMet) is an important, metabolically pleiotropic molecule
that participates in multiple cellular reactions as the precursor for the synthesis of glutathione …

Background/Aim: The efficacy of S-adenosylmethionine (AdoMet) in the treatment of liver
cell injury has been demonstrated in several experimental models. The aim of this study was …

Liver-specific and nonliver-specific methionine adenosyltransferases (MATs) are products of
two genes, MAT1A and MAT2A, respectively, that catalyze the formation of S …

Alcoholic liver disease (ALD) develops as a consequence of priming and sensitizing mecha
nisms rendered by cross‐interactions of primary mech anistic factors and secondary risk …

In animals, protein S-nitrosylation, the covalent attachment of NO to the thiol group of
cysteine residues, is an intensively investigated posttranslational modification, which …

An enzyme isolated from rat liver cytosol (native molecular mass 78.3 kDa; polypeptide
molecular mass 42.5 kDa) is capable of catalysing the NADH/NADPH-dependent …

During the fifteen years since the bestselling first edition of Folate in Health and Disease
was published, there have been thousands of new research studies related to folate and its …