The gut microbiome in Alzheimer's disease: what we know and what remains to be explored
Abstract Alzheimer's disease (AD), the most common cause of dementia, results in a
sustained decline in cognition. There are currently few effective disease modifying therapies …
sustained decline in cognition. There are currently few effective disease modifying therapies …
Sleep disturbances increase the risk of dementia: a systematic review and meta-analysis
L Shi, SJ Chen, MY Ma, YP Bao, Y Han, YM Wang… - Sleep medicine …, 2018 - Elsevier
Sleep disturbances and dementia are two common and significant health problems in older
adults. Investigations suggest that sleep disturbances might increase the risk of dementia …
adults. Investigations suggest that sleep disturbances might increase the risk of dementia …
Association between circadian rhythms and neurodegenerative diseases
Dysfunction in 24-h circadian rhythms is a common occurrence in ageing adults; however,
circadian rhythm disruptions are more severe in people with age-related neurodegenerative …
circadian rhythm disruptions are more severe in people with age-related neurodegenerative …
Rhythms of life: circadian disruption and brain disorders across the lifespan
RW Logan, CA McClung - Nature Reviews Neuroscience, 2019 - nature.com
Many processes in the human body—including brain function—are regulated over the 24-
hour cycle, and there are strong associations between disrupted circadian rhythms (for …
hour cycle, and there are strong associations between disrupted circadian rhythms (for …
Circadian rhythms in neurodegenerative disorders
M Nassan, A Videnovic - Nature Reviews Neurology, 2022 - nature.com
Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …
circadian rhythms that synchronize physiological and behavioural functions in humans. The …
Mechanisms linking circadian clocks, sleep, and neurodegeneration
ES Musiek, DM Holtzman - Science, 2016 - science.org
Disruptions of normal circadian rhythms and sleep cycles are consequences of aging and
can profoundly affect health. Accumulating evidence indicates that circadian and sleep …
can profoundly affect health. Accumulating evidence indicates that circadian and sleep …
Biological rhythm and chronotype: new perspectives in health
The circadian rhythm plays a fundamental role in regulating biological functions, including
sleep–wake preference, body temperature, hormonal secretion, food intake, and cognitive …
sleep–wake preference, body temperature, hormonal secretion, food intake, and cognitive …
Connections between sleep and cognition in older adults
K Yaffe, CM Falvey, T Hoang - The Lancet Neurology, 2014 - thelancet.com
Sleep disturbances and cognitive impairment are common in older adults. Mounting
evidence points to a potential connection between sleep and cognitive function. Findings …
evidence points to a potential connection between sleep and cognitive function. Findings …
Sleep, cognitive impairment, and Alzheimer's disease: a systematic review and meta-analysis
OM Bubu, M Brannick, J Mortimer, O Umasabor-Bubu… - Sleep, 2017 - academic.oup.com
Abstract Study Objectives: Mounting evidence implicates disturbed sleep or lack of sleep as
one of the risk factors for Alzheimer's disease (AD), but the extent of the risk is uncertain. We …
one of the risk factors for Alzheimer's disease (AD), but the extent of the risk is uncertain. We …
Social jetlag and related risks for human health: a timely review
R Caliandro, AA Streng, LWM van Kerkhof… - Nutrients, 2021 - mdpi.com
The term social jetlag is used to describe the discrepancy between biological time,
determined by our internal body clock, and social times, mainly dictated by social obligations …
determined by our internal body clock, and social times, mainly dictated by social obligations …