There are well-established disparities in cancer incidence and outcomes by race/ethnicity
that result from the interplay between structural, socioeconomic, socio-environmental …

Next-generation sequencing (NGS) technology has expanded in the last decades with
significant improvements in the reliability, sequencing chemistry, pipeline analyses, data …

Stratification of women according to their risk of breast cancer based on polygenic risk
scores (PRSs) could improve screening and prevention strategies. Our aim was to develop …

Carbon quantum dots (CQDs) have emerged as promising materials for optoelectronic
applications on account of carbon's intrinsic merits of high stability, low cost, and …

Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as
BRCA1, and many common, mostly non-coding variants. However, much of the genetic …

Breast cancer susceptibility variants frequently show heterogeneity in associations by tumor
subtype,–. To identify novel loci, we performed a genome-wide association study including …

Deciphering the shared genetic basis of distinct cancers has the potential to elucidate
carcinogenic mechanisms and inform broadly applicable risk assessment efforts. Here, we …

To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-
genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence …

Abstract The NHGRI-EBI GWAS Catalog has provided data from published genome-wide
association studies since 2008. In 2015, the database was redesigned and relocated to …

Physical activity has been associated with lower risks of breast and colorectal cancer in
epidemiological studies; however, it is unknown if these associations are causal or …