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The biological applications of DNA nanomaterials: current challenges and future directions
W Ma, Y Zhan, Y Zhang, C Mao, X **e… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …
biological applications as driven by DNA nanotechnology in the past decades, including …
Chemo-physical Strategies to Advance the in Vivo Functionality of Targeted Nanomedicine: The Next Generation
The past few decades have witnessed an evolution of nanomedicine from biologically inert
entities to more smart systems, aimed at advancing in vivo functionality. However, we should …
entities to more smart systems, aimed at advancing in vivo functionality. However, we should …
A neutrophil mimicking metal-porphyrin-based nanodevice loaded with porcine pancreatic elastase for cancer therapy
T Cui, Y Zhang, G Qin, Y Wei, J Yang, Y Huang… - Nature …, 2023 - nature.com
Precise discrimination and eradication of cancer cells by immune cells independent of
antigen recognition is promising for solid tumor therapeutics, yet remains a tremendous …
antigen recognition is promising for solid tumor therapeutics, yet remains a tremendous …
DNA nanostructure-based nucleic acid probes: construction and biological applications
DX Wang, J Wang, YX Wang, YC Du, Y Huang… - Chemical …, 2021 - pubs.rsc.org
In recent years, DNA has been widely noted as a kind of material that can be used to
construct building blocks for biosensing, in vivo imaging, drug development, and disease …
construct building blocks for biosensing, in vivo imaging, drug development, and disease …
DNA nanostructures for exploring cell–cell communication
Y Wang, Y **ong, K Shi, CY Effah, L Song… - Chemical Society …, 2024 - pubs.rsc.org
The process of coordinating between the same or multiple types of cells to jointly execute
various instructions in a controlled and carefully regulated environment is a very appealing …
various instructions in a controlled and carefully regulated environment is a very appealing …
Harnessing engineered immune cells and bacteria as drug carriers for cancer immunotherapy
Immunotherapy continues to be in the spotlight of oncology therapy research in the past few
years and has been proven to be a promising option to modulate one's innate and adaptive …
years and has been proven to be a promising option to modulate one's innate and adaptive …
Aptamer-Based Nongenetic Reprogramming of CARs Enables Flexible Modulation of T Cell-Mediated Tumor Immunotherapy
Innovating the design of chimeric antigen receptors (CARs) beyond conventional structures
would be necessary to address the challenges of efficacy, safety, and applicability in T cell …
would be necessary to address the challenges of efficacy, safety, and applicability in T cell …
Fluid nanoporous microinterface enables multiscale-enhanced affinity interaction for tumor-derived extracellular vesicle detection
Q Niu, J Gao, K Zhao, X Chen, X Lin, C Huang… - Proceedings of the …, 2022 - pnas.org
Tumor-derived extracellular vesicles (T-EVs) represent valuable markers for tumor diagnosis
and treatment guidance. However, nanoscale sizes and the low abundance of marker …
and treatment guidance. However, nanoscale sizes and the low abundance of marker …
Cell surface-localized imaging and sensing
Systematically dissecting the molecular basis of the cell surface as well as its related
biological activities is considered as one of the most cutting-edge fields in fundamental …
biological activities is considered as one of the most cutting-edge fields in fundamental …
New opportunities for immunomodulation of the tumour microenvironment using chemical tools
JY Su, WH Li, YM Li - Chemical Society Reviews, 2022 - pubs.rsc.org
Immunotherapy is recognised as an attractive method for the treatment of cancer, and
numerous treatment strategies have emerged over recent years. Investigations of the tumour …
numerous treatment strategies have emerged over recent years. Investigations of the tumour …